#history, #channel, #waiting, #registry-eligibility, #stewardship, #limits, #tracks, #unmet-need, #ptc-simulator, #aso-splice-explorer, #care-team-questions { scroll-margin-top: 5rem; }

.subnav-strip {
  position: sticky;
  top: 0;
  z-index: 15;
  background: rgba(5, 5, 5, 0.88);
  backdrop-filter: blur(12px);
  -webkit-backdrop-filter: blur(12px);
  border-bottom: 1px solid var(--border-glass);
  padding: 0.5rem 0;
  margin-bottom: 2rem;
}
.subnav-inner {
  display: flex;
  align-items: center;
  gap: 1rem;
  overflow-x: auto;
  scrollbar-width: none;
  -webkit-overflow-scrolling: touch;
}
.subnav-inner::-webkit-scrollbar { display: none; }
.subnav-label {
  font: 600 0.75rem var(--font-mono);
  color: var(--muted);
  text-transform: uppercase;
  letter-spacing: 0.05em;
  white-space: nowrap;
}
.subnav-list {
  display: flex;
  align-items: center;
  gap: 0.5rem;
  list-style: none;
  margin: 0;
  padding: 0;
  white-space: nowrap;
}
.subnav-link {
  display: inline-block;
  padding: 0.35rem 0.85rem;
  border-radius: 20px;
  border: 1px solid transparent;
  font: 500 0.84rem var(--font-body);
  color: var(--ink-secondary);
  text-decoration: none;
  background: rgba(255, 255, 255, 0.03);
  transition: all 0.2s ease;
}
.subnav-link:hover, .subnav-link:focus-visible {
  color: var(--ink-primary);
  border-color: rgba(0, 243, 255, 0.4);
  background: rgba(0, 243, 255, 0.08);
}
.subnav-link.is-active, .subnav-link[aria-current="location"] {
  color: var(--neon-cyan);
  border-color: rgba(0, 243, 255, 0.6);
  background: rgba(0, 243, 255, 0.12);
  font-weight: 600;
}
.subnav-rail {
  display: block;
}

.widescreen-feature-split {
  display: grid;
  grid-template-columns: 1fr;
  gap: 2rem;
  align-items: start;
}
@media (min-width: 64rem) {
  .widescreen-feature-split {
    grid-template-columns: minmax(0, 1.15fr) minmax(0, 0.85fr);
    gap: 2.5rem;
  }
}
.model-preview-card {
  padding: 1.5rem;
  border: 1px solid var(--border-glass);
  border-radius: 12px;
  background: rgba(12, 12, 12, 0.75);
  backdrop-filter: blur(10px);
  -webkit-backdrop-filter: blur(10px);
}
.model-preview-badge {
  display: inline-block;
  font: 600 0.72rem var(--font-mono);
  color: var(--neon-cyan);
  background: rgba(0, 243, 255, 0.1);
  padding: 0.2rem 0.6rem;
  border-radius: 4px;
  border: 1px solid rgba(0, 243, 255, 0.25);
  margin-bottom: 0.75rem;
  letter-spacing: 0.04em;
}
.model-preview-title {
  font-size: 1.15rem;
  font-weight: 600;
  color: var(--ink-primary);
  margin: 0 0 0.5rem;
}
.model-preview-desc {
  font-size: 0.88rem;
  color: var(--ink-secondary);
  margin: 0 0 1rem;
  line-height: 1.5;
}
.model-structures-list {
  list-style: none;
  margin: 0 0 1.25rem;
  padding: 0;
  display: grid;
  gap: 0.5rem;
}
.model-structures-list li {
  display: flex;
  align-items: baseline;
  gap: 0.6rem;
  font-size: 0.85rem;
  color: var(--ink-secondary);
}
.struct-id {
  font: 600 0.8rem var(--font-mono);
  color: var(--lime);
  background: rgba(237, 189, 69, 0.1);
  padding: 0.1rem 0.4rem;
  border-radius: 3px;
  border: 1px solid rgba(237, 189, 69, 0.25);
}
.struct-desc {
  font-size: 0.84rem;
}
.model-preview-cta {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  width: 100%;
  min-height: 2.75rem;
  padding: 0.65rem 1rem;
  border-radius: 8px;
  border: 1px solid var(--neon-cyan);
  background: rgba(0, 243, 255, 0.1);
  color: var(--neon-cyan);
  font: 600 0.88rem var(--font-mono);
  text-decoration: none;
  transition: all 0.2s ease;
}
.model-preview-cta:hover, .model-preview-cta:focus-visible {
  background: var(--neon-cyan);
  color: var(--bg-dark);
}

.research-showcase-wrap {
  width: min(100% - 2rem, var(--wide));
  margin-inline: auto;
}
.research-showcase-intro {
  max-width: 48rem;
  color: var(--ink-secondary);
  margin: 0.5rem 0 1.5rem;
  font-size: 0.96rem;
}
.research-showcase-grid-wrap {
  margin: 1.5rem auto;
}
.research-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
  gap: 1.25rem;
  list-style: none;
  margin: 0;
  padding: 0;
}
.research-card {
  padding: 1.4rem 1.5rem;
  border: 1px solid var(--border-glass);
  border-radius: 12px;
  background: rgba(10, 10, 10, 0.78);
  backdrop-filter: blur(10px);
  -webkit-backdrop-filter: blur(10px);
  display: flex;
  flex-direction: column;
  justify-content: space-between;
  transition: border-color 0.2s ease, box-shadow 0.2s ease, transform 0.2s ease;
}
.research-card:hover {
  border-color: rgba(0, 243, 255, 0.4);
  box-shadow: 0 6px 24px rgba(0, 243, 255, 0.08);
}
.card-header {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 0.5rem;
  margin-bottom: 0.75rem;
}
.card-badge {
  font: 600 0.72rem var(--font-mono);
  padding: 0.15rem 0.55rem;
  border-radius: 4px;
  letter-spacing: 0.03em;
}
.badge-track-a {
  color: var(--neon-cyan);
  background: rgba(0, 243, 255, 0.1);
  border: 1px solid rgba(0, 243, 255, 0.25);
}
.badge-track-b {
  color: var(--lime);
  background: rgba(237, 189, 69, 0.1);
  border: 1px solid rgba(237, 189, 69, 0.25);
}
.badge-microbiology {
  color: var(--coral);
  background: rgba(240, 120, 67, 0.1);
  border: 1px solid rgba(240, 120, 67, 0.25);
}
.badge-clinical {
  color: #a78bfa;
  background: rgba(167, 139, 250, 0.1);
  border: 1px solid rgba(167, 139, 250, 0.25);
}
.card-task {
  font: 500 0.75rem var(--font-mono);
  color: var(--muted);
}
.card-title {
  font-size: 1.08rem;
  font-weight: 600;
  color: var(--ink-primary);
  margin: 0 0 0.6rem;
  line-height: 1.35;
}
.card-body {
  font-size: 0.9rem;
  color: var(--ink-secondary);
  line-height: 1.55;
  margin: 0 0 1.25rem;
  flex-grow: 1;
}
.card-footer {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 0.45rem;
  padding-top: 0.85rem;
  border-top: 1px solid rgba(255, 255, 255, 0.06);
}
.card-pill {
  font: 500 0.76rem var(--font-mono);
  color: var(--ink-secondary);
  background: rgba(255, 255, 255, 0.04);
  padding: 0.15rem 0.5rem;
  border-radius: 3px;
  border: 1px solid rgba(255, 255, 255, 0.08);
}
a.card-pill {
  display: inline-flex;
  align-items: center;
  min-height: 2.25rem;
  padding: 0.35rem 0.65rem;
  color: var(--neon-cyan);
  border-color: rgba(0, 243, 255, 0.35);
}
.research-showcase-disclaimer {
  font-size: 0.85rem;
  color: var(--muted);
  margin-top: 1rem;
}

.research-card[id] {
  scroll-margin-top: 5.5rem;
}
.showcase-target-anchors {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 0.5rem 0.75rem;
  margin: 0.85rem 0 1.25rem;
  font: 500 0.8rem var(--font-mono);
}
.anchor-jump-label {
  color: var(--muted);
  font-size: 0.75rem;
  text-transform: uppercase;
  letter-spacing: 0.05em;
}
.anchor-jump-link {
  display: inline-flex;
  align-items: center;
  min-height: 2.25rem;
  color: var(--neon-cyan);
  text-decoration: none;
  background: rgba(0, 243, 255, 0.06);
  padding: 0.3rem 0.65rem;
  border-radius: 4px;
  border: 1px solid rgba(0, 243, 255, 0.2);
  transition: border-color 0.15s ease, background 0.15s ease;
}
.anchor-jump-link:hover, .anchor-jump-link:focus-visible {
  background: rgba(0, 243, 255, 0.14);
  border-color: rgba(0, 243, 255, 0.5);
}
.anchor-jump-link.is-active, .anchor-jump-link[aria-current="location"] {
  color: #fff;
  border-color: rgba(0, 243, 255, 0.8);
  background: rgba(0, 243, 255, 0.25);
  box-shadow: 0 0 10px rgba(0, 243, 255, 0.2);
}

@media (prefers-reduced-motion: reduce) {
  .subnav-link, .model-preview-cta, .research-card, .anchor-jump-link {
    transition: none;
  }
}

.registry-cards-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(18rem, 1fr));
  gap: 1.25rem;
  margin: 1.5rem 0;
}
.registry-card {
  padding: 1.25rem;
  border-radius: 8px;
  background: rgba(255, 255, 255, 0.03);
  border: 1px solid rgba(255, 255, 255, 0.08);
  display: flex;
  flex-direction: column;
}
.registry-card-header {
  display: flex;
  align-items: center;
  gap: 0.6rem;
  margin-bottom: 0.75rem;
}
.registry-flag {
  font-size: 1.25rem;
}
.registry-name {
  font: 600 0.95rem var(--font-body);
  color: var(--ink-primary);
}
.registry-stats {
  font-size: 0.9rem;
  line-height: 1.5;
  color: var(--ink-secondary);
  margin-bottom: 0.75rem;
  flex-grow: 1;
}
.registry-cite {
  font: 500 0.75rem var(--font-mono);
  color: var(--muted);
  margin: 0;
}

#ptc-simulator { scroll-margin-top: 4.8rem; }

.ptc-sim-wrap {
  margin: 3.5rem auto;
}

.ptc-sim-container {
  background: radial-gradient(circle at 15% 20%, rgba(230, 45, 70, 0.05), transparent 45%),
              radial-gradient(circle at 85% 80%, rgba(0, 243, 255, 0.04), transparent 50%),
              rgba(10, 10, 12, 0.85);
  border: 1px solid rgba(255, 255, 255, 0.1);
  border-radius: 12px;
  padding: 2rem;
  backdrop-filter: blur(16px);
  -webkit-backdrop-filter: blur(16px);
  box-shadow: 0 16px 40px rgba(0, 0, 0, 0.5);
}

.ptc-sim-header {
  display: flex;
  flex-direction: column;
  align-items: center;
  text-align: center;
  gap: 1.25rem;
  border-bottom: 1px solid rgba(255, 255, 255, 0.08);
  padding-bottom: 1.75rem;
  margin-bottom: 2rem;
}

.ptc-sim-title-group {
  display: flex;
  flex-direction: column;
  align-items: center;
  text-align: center;
  width: 100%;
}

.ptc-sim-title-group h2,
.ptc-sim-title-group h3 {
  font: 600 clamp(1.4rem, 2.6vw, 2.1rem) var(--font-display);
  color: var(--ink-primary);
  margin: 0 0 0.6rem 0;
  text-align: center;
  max-width: 32ch;
  line-height: 1.2;
}

.ptc-sim-sub {
  font: 400 0.95rem var(--font-body);
  color: var(--ink-secondary);
  max-width: 46rem;
  margin: 0 auto;
  line-height: 1.55;
  text-align: center;
}

.ptc-variant-switch {
  display: inline-flex;
  flex-wrap: wrap;
  justify-content: center;
  background: rgba(255, 255, 255, 0.04);
  border: 1px solid rgba(255, 255, 255, 0.12);
  border-radius: 8px;
  padding: 0.25rem;
  gap: 0.25rem;
  margin: 0 auto;
}

.ptc-variant-btn {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  min-height: 2.5rem;
  background: transparent;
  border: none;
  color: var(--ink-secondary);
  font: 600 0.85rem var(--font-mono);
  padding: 0.5rem 1rem;
  border-radius: 6px;
  cursor: pointer;
  transition: all 0.2s ease;
}

.ptc-variant-btn:hover {
  color: var(--ink-primary);
}

.ptc-variant-btn.active {
  background: rgba(230, 45, 70, 0.22);
  color: #ff8598;
  border: 1px solid rgba(230, 45, 70, 0.45);
  box-shadow: 0 0 12px rgba(230, 45, 70, 0.25);
}

.ptc-sim-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(18rem, 1fr));
  gap: 2rem;
  margin-bottom: 2rem;
}

.ptc-controls-col {
  display: flex;
  flex-direction: column;
  gap: 1.5rem;
}

.ptc-slider-control {
  background: rgba(255, 255, 255, 0.02);
  border: 1px solid rgba(255, 255, 255, 0.06);
  border-radius: 8px;
  padding: 1.25rem;
}

.ptc-slider-label-row {
  display: flex;
  justify-content: space-between;
  align-items: center;
  margin-bottom: 0.5rem;
}

.ptc-slider-title {
  font: 600 0.9rem var(--font-body);
  color: var(--ink-primary);
}

.ptc-slider-badge {
  font: 700 0.95rem var(--font-mono);
  color: var(--neon-cyan);
}

.ptc-slider-desc {
  font: 400 0.8rem var(--font-body);
  color: var(--muted);
  margin-bottom: 0.85rem;
  line-height: 1.4;
}

.ptc-range-input {
  width: 100%;
  min-height: 2.25rem;
  accent-color: #ff3355;
  cursor: pointer;
}

.ptc-gauge-col {
  display: flex;
  flex-direction: column;
  gap: 1.5rem;
}

.ptc-gauge-card {
  background: rgba(15, 17, 23, 0.8);
  border: 1px solid rgba(255, 255, 255, 0.1);
  border-radius: 10px;
  padding: 1.5rem;
  text-align: center;
  position: relative;
  overflow: hidden;
}

.ptc-gauge-title {
  font: 600 0.85rem var(--font-mono);
  color: var(--muted);
  text-transform: uppercase;
  letter-spacing: 0.05em;
  margin-bottom: 0.5rem;
}

.ptc-gauge-value {
  font: 700 3.2rem var(--font-mono);
  line-height: 1.1;
  margin: 0.25rem 0;
  transition: color 0.3s ease;
}

.ptc-gauge-value.curative-achieved {
  color: #39e58c;
  text-shadow: 0 0 20px rgba(57, 229, 140, 0.4);
}

.ptc-gauge-value.curative-subthreshold {
  color: #ff9800;
}

.ptc-gauge-status {
  font: 600 0.85rem var(--font-body);
  margin: 0.5rem 0 1rem 0;
}

.ptc-gauge-status.status-pass {
  color: #5cdba0;
}

.ptc-gauge-status.status-fail {
  color: #ffb74d;
}

.ptc-metrics-row {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(6.5rem, 1fr));
  gap: 0.75rem;
  padding-top: 1rem;
  border-top: 1px solid rgba(255, 255, 255, 0.08);
}

.ptc-submetric {
  text-align: center;
}

.ptc-submetric-label {
  font: 500 0.72rem var(--font-mono);
  color: var(--muted);
  display: block;
  margin-bottom: 0.25rem;
}

.ptc-submetric-val {
  font: 600 0.95rem var(--font-mono);
  color: var(--ink-primary);
}

.ptc-badge {
  display: inline-block;
  font: 600 0.7rem var(--font-mono);
  padding: 0.2rem 0.5rem;
  border-radius: 4px;
}

.ptc-badge.optimal_safety_window {
  background: rgba(57, 229, 140, 0.15);
  color: #39e58c;
  border: 1px solid rgba(57, 229, 140, 0.3);
}

.ptc-badge.elevated_off_target_risk {
  background: rgba(255, 152, 0, 0.15);
  color: #ff9800;
  border: 1px solid rgba(255, 152, 0, 0.3);
}

.ptc-badge.proteotoxic_hazard {
  background: rgba(244, 67, 54, 0.15);
  color: #f44336;
  border: 1px solid rgba(244, 67, 54, 0.3);
}

.ptc-badge.sub_therapeutic {
  background: rgba(255, 255, 255, 0.08);
  color: var(--muted);
}

.ptc-cryo-card {
  background: rgba(255, 255, 255, 0.02);
  border: 1px solid rgba(0, 243, 255, 0.2);
  border-radius: 8px;
  padding: 1.25rem;
}

.ptc-cryo-title {
  font: 600 0.85rem var(--font-mono);
  color: var(--neon-cyan);
  display: flex;
  align-items: center;
  gap: 0.5rem;
  margin-bottom: 0.6rem;
}

.ptc-cryo-detail {
  font: 400 0.82rem var(--font-body);
  color: var(--ink-secondary);
  line-height: 1.5;
  margin: 0 0 0.5rem 0;
}

.ptc-cryo-metric {
  font: 500 0.78rem var(--font-mono);
  color: var(--muted);
  line-height: 1.4;
  margin: 0;
}

.ptc-presets-bar {
  display: flex;
  align-items: center;
  justify-content: center;
  gap: 0.6rem;
  flex-wrap: wrap;
  padding-top: 1.25rem;
  border-top: 1px solid rgba(255, 255, 255, 0.08);
}

.ptc-presets-label {
  font: 600 0.78rem var(--font-mono);
  color: var(--muted);
  text-transform: uppercase;
  margin-right: 0.25rem;
}

.ptc-preset-btn {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  min-height: 2.5rem;
  background: rgba(255, 255, 255, 0.04);
  border: 1px solid rgba(255, 255, 255, 0.1);
  color: var(--ink-primary);
  font: 500 0.8rem var(--font-body);
  padding: 0.45rem 0.85rem;
  border-radius: 6px;
  cursor: pointer;
  transition: all 0.2s ease;
}

.ptc-preset-btn:hover {
  background: rgba(0, 243, 255, 0.1);
  border-color: rgba(0, 243, 255, 0.3);
  color: var(--neon-cyan);
}

.ptc-preset-btn.highlight-curative {
  background: rgba(230, 45, 70, 0.15);
  border-color: rgba(230, 45, 70, 0.4);
  color: #ff8598;
}

.ptc-preset-btn.highlight-curative:hover {
  background: rgba(230, 45, 70, 0.25);
  border-color: rgba(230, 45, 70, 0.6);
}

.ptc-disclaimer-note {
  margin-top: 1rem;
  font: 400 0.76rem var(--font-body);
  color: var(--muted);
  line-height: 1.4;
  text-align: center;
  max-width: 52rem;
  margin-left: auto;
  margin-right: auto;
}

.ptc-track-badge {
  display: inline-block;
  margin: 0 auto 0.5rem auto;
}

.ptc-badge-wrap {
  margin-top: 0.75rem;
}

.ptc-cryo-metric.ptc-allosteric {
  margin-top: 0.4rem;
  color: var(--ink-secondary);
}

.tracks-section {
  padding-top: 3.5rem;
  padding-bottom: 2.5rem;
  border-bottom: 1px solid rgba(255, 255, 255, 0.08);
}

.tracks-hub-grid {
  display: grid;
  grid-template-columns: repeat(2, 1fr);
  gap: 1.5rem;
  margin-top: 2rem;
}

@media (max-width: 860px) {
  .tracks-hub-grid {
    grid-template-columns: 1fr;
  }
}

.track-card {
  background: rgba(255, 255, 255, 0.02);
  border: 1px solid rgba(255, 255, 255, 0.1);
  border-radius: 12px;
  padding: 1.75rem;
  display: flex;
  flex-direction: column;
  position: relative;
  transition: border-color 0.2s ease, transform 0.2s ease, box-shadow 0.2s ease;
}

.track-card:hover {
  transform: translateY(-2px);
  border-color: rgba(255, 255, 255, 0.22);
}

.track-card.track-a {
  border-top: 3px solid var(--neon-cyan);
}

.track-card.track-a:hover {
  box-shadow: 0 8px 32px rgba(0, 243, 255, 0.1);
}

.track-card.track-b {
  border-top: 3px solid var(--lime);
}

.track-card.track-b:hover {
  box-shadow: 0 8px 32px rgba(237, 189, 69, 0.1);
}

.track-card-header {
  display: flex;
  align-items: center;
  justify-content: space-between;
  margin-bottom: 1rem;
}

.track-id {
  font: 500 0.76rem var(--font-mono);
  color: var(--muted);
  text-transform: uppercase;
  letter-spacing: 0.04em;
}

.track-card h3 {
  font-size: 1.35rem;
  font-weight: 600;
  color: var(--ink-primary);
  margin: 0 0 0.75rem;
  line-height: 1.3;
}

.track-desc {
  font-size: 0.95rem;
  color: var(--ink-secondary);
  line-height: 1.55;
  margin: 0 0 1.25rem;
}

.track-features {
  list-style: none;
  padding: 0;
  margin: 0 0 1.5rem 0;
  display: flex;
  flex-direction: column;
  gap: 0.6rem;
  flex-grow: 1;
}

.track-features li {
  font-size: 0.88rem;
  color: var(--ink-secondary);
  line-height: 1.45;
  position: relative;
  padding-left: 1.2rem;
}

.track-features li::before {
  content: "›";
  position: absolute;
  left: 0;
  color: var(--muted);
  font-weight: 700;
}

.track-actions {
  display: flex;
  align-items: center;
  gap: 0.5rem 0.6rem;
  flex-wrap: wrap;
  padding-top: 1rem;
  border-top: 1px solid rgba(255, 255, 255, 0.06);
}

.track-cta {
  display: inline-flex;
  align-items: center;
  min-height: 2.4rem;
  gap: 0.4rem;
  background: rgba(255, 255, 255, 0.09);
  border: 1px solid rgba(255, 255, 255, 0.16);
  color: var(--ink-primary);
  font: 600 0.82rem var(--font-mono);
  padding: 0.45rem 0.95rem;
  border-radius: 6px;
  text-decoration: none;
  transition: all 0.2s ease;
}

.track-card.track-a .track-cta:hover {
  background: var(--neon-cyan);
  border-color: var(--neon-cyan);
  color: #050505;
}

.track-card.track-b .track-cta:hover {
  background: var(--lime);
  border-color: var(--lime);
  color: #050505;
}

.track-link {
  display: inline-flex;
  align-items: center;
  min-height: 2.15rem;
  padding: 0.3rem 0.68rem;
  border: 1px solid rgba(255, 255, 255, 0.12);
  border-radius: 6px;
  background: rgba(255, 255, 255, 0.03);
  font: 500 0.78rem var(--font-mono);
  color: var(--ink-secondary);
  text-decoration: none;
  transition: border-color 0.18s ease, color 0.18s ease, background 0.18s ease;
}

.track-link:hover {
  color: var(--neon-cyan);
  border-color: rgba(0, 243, 255, 0.45);
  background: rgba(0, 243, 255, 0.08);
}

.unmet-need-section {
  padding-top: 3.5rem;
  padding-bottom: 2.5rem;
}

.ecfspr-explorer-card {
  margin-top: 2rem;
  margin-bottom: 2rem;
  background: rgba(12, 15, 22, 0.85);
  border: 1px solid rgba(255, 255, 255, 0.12);
  border-top: 3px solid var(--lime);
  border-radius: 12px;
  padding: 1.5rem;
  display: flex;
  flex-direction: column;
  gap: 1.25rem;
  max-width: 100%;
  box-sizing: border-box;
  overflow: hidden;
}

.ecfspr-explorer-header h3 {
  font-size: 1.22rem;
  font-weight: 600;
  color: var(--ink-primary);
  margin: 0.6rem 0 0.5rem;
  line-height: 1.3;
  overflow-wrap: anywhere;
}

.ecfspr-explorer-sub {
  font-size: 0.9rem;
  color: var(--ink-secondary);
  line-height: 1.55;
  margin: 0;
  overflow-wrap: anywhere;
}

.ecfspr-dimension-block {
  background: rgba(255, 255, 255, 0.02);
  border: 1px solid rgba(255, 255, 255, 0.08);
  border-radius: 10px;
  padding: 1.1rem;
  min-width: 0;
  max-width: 100%;
  box-sizing: border-box;
}

.ecfspr-dim-header {
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  align-items: center;
  gap: 0.75rem;
  margin-bottom: 1rem;
}

.ecfspr-dim-label {
  display: block;
  font: 600 0.78rem var(--font-mono);
  color: var(--lime);
  text-transform: uppercase;
  letter-spacing: 0.04em;
  margin-bottom: 0.35rem;
  overflow-wrap: anywhere;
}

.ecfspr-dim-desc {
  font-size: 0.84rem;
  color: var(--muted);
  margin: 0 0 0.85rem;
  line-height: 1.45;
  overflow-wrap: anywhere;
}

.ecfspr-year-switch,
.ecfspr-scope-buttons {
  display: flex;
  flex-wrap: wrap;
  gap: 0.4rem;
  max-width: 100%;
}

.ecfspr-pill-btn,
.ecfspr-scope-btn {
  display: inline-flex;
  align-items: center;
  min-height: 2.25rem;
  background: rgba(255, 255, 255, 0.04);
  border: 1px solid rgba(255, 255, 255, 0.14);
  color: var(--ink-secondary);
  font: 600 0.75rem var(--font-mono);
  padding: 0.38rem 0.65rem;
  border-radius: 6px;
  cursor: pointer;
  max-width: 100%;
  text-align: left;
  overflow-wrap: anywhere;
  transition: background 0.15s ease, color 0.15s ease, border-color 0.15s ease;
}

.ecfspr-pill-btn:hover,
.ecfspr-scope-btn:hover {
  border-color: rgba(255, 255, 255, 0.32);
  color: var(--ink-primary);
}

.ecfspr-pill-btn.active,
.ecfspr-scope-btn.active {
  background: rgba(237, 189, 69, 0.18);
  border-color: var(--lime);
  color: var(--ink-primary);
}

.ecfspr-kpi-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(9.5rem, 1fr));
  gap: 0.75rem;
}

.ecfspr-kpi-box {
  background: rgba(5, 7, 11, 0.65);
  border: 1px solid rgba(255, 255, 255, 0.07);
  border-radius: 8px;
  padding: 0.75rem 0.85rem;
  display: flex;
  flex-direction: column;
  gap: 0.25rem;
  min-width: 0;
  overflow-wrap: anywhere;
}

.ecfspr-kpi-label {
  font: 500 0.72rem var(--font-mono);
  color: var(--muted);
}

.ecfspr-kpi-val {
  font: 700 1.05rem var(--font-mono);
  color: var(--ink-primary);
}

.ecfspr-kpi-scope {
  font: 400 0.68rem var(--font-mono);
  color: var(--neon-cyan);
  overflow-wrap: anywhere;
}

.ecfspr-two-col-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 1.1rem;
}

@media (max-width: 860px) {
  .ecfspr-two-col-grid {
    grid-template-columns: 1fr;
  }
}

.ecfspr-scope-detail,
.ecfspr-country-readout {
  margin-top: 0.85rem;
  background: rgba(5, 7, 11, 0.65);
  border: 1px solid rgba(255, 255, 255, 0.08);
  border-radius: 8px;
  padding: 0.8rem 0.9rem;
  min-width: 0;
  overflow-wrap: anywhere;
}

.ecfspr-scope-detail-top {
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  align-items: center;
  gap: 0.45rem;
  margin-bottom: 0.45rem;
}

.ecfspr-scope-pill {
  font: 600 0.75rem var(--font-mono);
  color: var(--neon-cyan);
}

.ecfspr-scope-rule,
.ecfspr-country-note {
  font-size: 0.8rem;
  color: var(--ink-secondary);
  margin: 0;
  line-height: 1.45;
  overflow-wrap: anywhere;
}

.ecfspr-country-control {
  display: flex;
  flex-direction: column;
  gap: 0.4rem;
  min-width: 0;
}

.ecfspr-country-label {
  font: 500 0.75rem var(--font-mono);
  color: var(--muted);
}

.ecfspr-select {
  min-height: 2.5rem;
  background: rgba(5, 7, 11, 0.9);
  color: var(--ink-primary);
  border: 1px solid rgba(255, 255, 255, 0.2);
  border-radius: 6px;
  padding: 0.42rem 0.55rem;
  font: 500 0.8rem var(--font-mono);
  width: 100%;
  max-width: 100%;
  box-sizing: border-box;
}

.ecfspr-country-stat-row {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(6.5rem, 1fr));
  gap: 0.55rem;
  margin-bottom: 0.55rem;
}

.ecfspr-mini-k {
  display: block;
  font: 500 0.68rem var(--font-mono);
  color: var(--muted);
  text-transform: uppercase;
}

.ecfspr-xray-panel {
  background: rgba(5, 8, 14, 0.92);
  border: 1px solid rgba(0, 243, 255, 0.24);
  border-radius: 10px;
  padding: 1rem;
  display: flex;
  flex-direction: column;
  gap: 0.65rem;
  min-width: 0;
  max-width: 100%;
  box-sizing: border-box;
  overflow-wrap: anywhere;
}

.ecfspr-xray-header {
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  align-items: center;
  gap: 0.5rem;
}

.ecfspr-xray-title {
  font: 600 0.78rem var(--font-mono);
  color: var(--neon-cyan);
  text-transform: uppercase;
  letter-spacing: 0.04em;
}

.ecfspr-xray-link {
  display: inline-flex;
  align-items: center;
  min-height: 2.25rem;
  font: 600 0.76rem var(--font-mono);
  color: var(--lime);
  text-decoration: none;
}

.ecfspr-xray-link:hover {
  text-decoration: underline;
}

.ecfspr-xray-meta-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(11rem, 1fr));
  gap: 0.55rem;
  font-size: 0.78rem;
  color: var(--ink-secondary);
}

.ecfspr-xray-meta-grid code {
  font: 500 0.72rem var(--font-mono);
  color: var(--ink-primary);
  word-break: break-all;
}

.ecfspr-xray-quotes {
  border-top: 1px solid rgba(255, 255, 255, 0.08);
  padding-top: 0.6rem;
  display: flex;
  flex-direction: column;
  gap: 0.4rem;
}

.ecfspr-quote-line {
  font-size: 0.78rem;
  color: var(--ink-secondary);
  margin: 0;
  line-height: 1.4;
  overflow-wrap: anywhere;
}

.ecfspr-xray-boundary {
  font-size: 0.74rem;
  color: var(--muted);
  margin: 0;
  border-top: 1px solid rgba(255, 255, 255, 0.06);
  padding-top: 0.5rem;
}

@media (max-width: 640px) {
  .ptc-sim-container {
    padding: 1.25rem 1rem;
  }
  .track-card {
    padding: 1.35rem 1.15rem;
  }
  .track-actions {
    display: grid;
    grid-template-columns: repeat(2, minmax(0, 1fr));
    gap: 0.45rem;
  }
  .track-cta {
    grid-column: 1 / -1;
    justify-content: center;
    text-align: center;
  }
  .track-link {
    justify-content: center;
    text-align: center;
    font-size: 0.72rem;
    padding: 0.35rem 0.4rem;
    line-height: 1.25;
  }
  .ptc-preset-btn,
  .ptc-variant-btn,
  .anchor-jump-link,
  .ecfspr-pill-btn,
  .ecfspr-scope-btn,
  .track-cta,
  .track-link {
    min-height: 2.5rem;
  }
}

@media (max-width: 520px) {
  .ecfspr-explorer-card {
    padding: 1rem;
  }
  .ecfspr-dimension-block {
    padding: 0.85rem;
  }
  .ecfspr-kpi-grid,
  .ecfspr-xray-meta-grid,
  .ecfspr-country-stat-row {
    grid-template-columns: 1fr;
  }
}

.scale-rail-wrap {
  margin: 1.5rem 0 2rem;
  padding: 1.15rem 1.25rem;
  border: 1px solid rgba(0, 243, 255, 0.22);
  border-radius: 12px;
  background: linear-gradient(135deg, rgba(8, 12, 20, 0.9), rgba(14, 10, 22, 0.88));
}
.scale-rail-head {
  display: flex;
  flex-wrap: wrap;
  align-items: baseline;
  justify-content: space-between;
  gap: 0.4rem 1rem;
  margin-bottom: 0.85rem;
}
.scale-rail-title {
  font: 600 0.78rem var(--font-mono);
  color: var(--neon-cyan);
  text-transform: uppercase;
  letter-spacing: 0.06em;
  margin: 0;
}
.scale-rail-sub {
  font: 400 0.78rem var(--font-mono);
  color: var(--ink-secondary);
  margin: 0;
}
.scale-rail {
  list-style: none;
  margin: 0;
  padding: 0;
  display: grid;
  grid-template-columns: repeat(6, minmax(0, 1fr));
  gap: 0.6rem;
}
.scale-stop {
  display: flex;
}
.scale-stop a {
  display: flex;
  flex-direction: column;
  justify-content: space-between;
   gap: 0.3rem;
  width: 100%;
  min-height: 2.75rem;
  padding: 0.65rem 0.7rem;
  border: 1px solid rgba(255, 255, 255, 0.12);
  border-top: 2px solid var(--neon-cyan);
  border-radius: 8px;
  background: rgba(255, 255, 255, 0.025);
  text-decoration: none;
  color: var(--ink-primary);
  transition: border-color 0.2s ease, background 0.2s ease, transform 0.2s ease;
}
.scale-stop:nth-child(even) a {
  border-top-color: var(--lime);
}
.scale-stop a:hover, .scale-stop a:focus-visible {
  border-color: var(--neon-cyan);
  background: rgba(0, 243, 255, 0.09);
  transform: translateY(-2px);
}
.scale-step-k {
  font: 600 0.68rem var(--font-mono);
  color: var(--lime);
  text-transform: uppercase;
  letter-spacing: 0.04em;
}
.scale-step-name {
  font: 600 0.86rem var(--font-display);
  color: var(--ink-primary);
  line-height: 1.25;
}
.scale-step-meta {
  font: 400 0.72rem var(--font-mono);
  color: var(--ink-secondary);
  line-height: 1.35;
}
@media (max-width: 1024px) {
  .scale-rail {
    grid-template-columns: repeat(3, minmax(0, 1fr));
  }
}
@media (max-width: 640px) {
  .scale-rail {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }
}
@media (max-width: 420px) {
  .scale-rail {
    grid-template-columns: 1fr;
  }
}

.scale-stepper {
  margin: 0.85rem 0 1.25rem;
  padding: 0.55rem 0.85rem;
  border: 1px solid rgba(0, 243, 255, 0.24);
  border-radius: 10px;
  background: rgba(8, 12, 20, 0.88);
  font-family: var(--font-mono);
}
.stepper-track {
  list-style: none;
  margin: 0;
  padding: 0;
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 0.5rem;
  align-items: stretch;
}
.stepper-step {
  display: flex;
  flex-direction: column;
  justify-content: center;
  gap: 0.15rem;
  width: 100%;
  min-width: 0;
  overflow: hidden;
  min-height: 2.75rem;
  padding: 0.4rem 0.65rem;
  border-radius: 7px;
  border: 1px solid rgba(255, 255, 255, 0.1);
  background: rgba(255, 255, 255, 0.025);
  color: var(--ink-primary);
  text-decoration: none;
  box-sizing: border-box;
  transition: border-color 0.18s ease, background 0.18s ease;
}
a.stepper-step:hover,
a.stepper-step:focus-visible {
  border-color: var(--neon-cyan);
  background: rgba(0, 243, 255, 0.09);
}
.stepper-current {
  border-color: rgba(237, 189, 69, 0.55);
  background: rgba(237, 189, 69, 0.1);
  text-align: center;
  align-items: center;
}
.stepper-next {
  text-align: right;
  align-items: flex-end;
}
.stepper-dir {
  font: 600 0.64rem var(--font-mono);
  color: var(--muted);
  text-transform: uppercase;
  letter-spacing: 0.05em;
}
.stepper-k {
  font: 700 0.72rem var(--font-mono);
  color: var(--neon-cyan);
}
.stepper-current .stepper-k {
  color: var(--lime);
}
.stepper-name {
  font: 500 0.76rem var(--font-body);
  color: var(--ink-secondary);
}
@media (max-width: 680px) {
  .scale-stepper {
    padding: 0.4rem 0.5rem;
    margin: 0.55rem 0 0.9rem;
  }
  .stepper-track {
    grid-template-columns: repeat(3, minmax(0, 1fr));
    gap: 0.35rem;
  }
  .stepper-step {
    padding: 0.32rem 0.42rem;
    min-height: 2.35rem;
    gap: 0.1rem;
  }
  .stepper-dir {
    font-size: 0.52rem;
    letter-spacing: 0.02em;
    white-space: nowrap;
    overflow: hidden;
    text-overflow: ellipsis;
    max-width: 100%;
  }
  .stepper-k {
    font-size: 0.6rem;
    white-space: nowrap;
    overflow: hidden;
    text-overflow: ellipsis;
    max-width: 100%;
  }
  .stepper-name {
    font-size: 0.65rem;
    white-space: nowrap;
    overflow: hidden;
    text-overflow: ellipsis;
    max-width: 100%;
  }
}

.aso-variant-switch {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
}

.aso-chem-toggle {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
  margin-top: 0.5rem;
}

.aso-chem-toggle .ptc-variant-btn {
  max-width: 100%;
  white-space: normal;
  text-align: center;
}

.aso-range-input {
  width: 100%;
  min-height: 2.25rem;
  accent-color: #00f3ff;
  cursor: pointer;
}

.aso-defect-summary-card {
  background: rgba(255, 255, 255, 0.03);
  border: 1px solid var(--border-glass);
  border-radius: 8px;
  padding: 1rem;
  margin-top: 1rem;
}

.aso-defect-title {
  font: 600 0.82rem var(--font-mono);
  color: var(--neon-cyan);
  text-transform: uppercase;
  letter-spacing: 0.05em;
}

.aso-defect-text {
  font: 400 0.88rem var(--font-body);
  color: var(--ink-secondary);
  margin: 0.4rem 0 0.6rem 0;
  line-height: 1.45;
}

.aso-stage-badge-wrap {
  margin-top: 0.4rem;
}

.aso-stage-badge {
  font: 600 0.72rem var(--font-mono);
  padding: 0.25rem 0.6rem;
  border-radius: 4px;
  display: inline-block;
  letter-spacing: 0.03em;
}

.aso-stage-badge.badge-clinical {
  color: #00f3ff;
  background: rgba(0, 243, 255, 0.12);
  border: 1px solid rgba(0, 243, 255, 0.35);
}

.aso-stage-badge.badge-preclinical {
  color: #ffd166;
  background: rgba(255, 209, 102, 0.12);
  border: 1px solid rgba(255, 209, 102, 0.35);
}

.care-questions-section {
  margin-top: 3.5rem;
  margin-bottom: 3.5rem;
}

.care-questions-header {
  margin-bottom: 1.5rem;
}

.care-questions-header .card-badge {
  display: inline-block;
  margin-bottom: 0.5rem;
}

.badge-track-b {
  color: #a78bfa;
  background: rgba(167, 139, 250, 0.12);
  border: 1px solid rgba(167, 139, 250, 0.3);
  font: 600 0.72rem var(--font-mono);
  padding: 0.2rem 0.55rem;
  border-radius: 4px;
  text-transform: uppercase;
  letter-spacing: 0.05em;
}

.care-questions-header h2 {
  font-size: 1.5rem;
  font-weight: 700;
  color: var(--ink-primary);
  margin: 0.25rem 0 0.5rem 0;
  line-height: 1.25;
}

.care-questions-sub {
  font: 400 0.95rem var(--font-body);
  color: var(--ink-secondary);
  margin: 0;
  line-height: 1.5;
  max-width: 52rem;
}

.care-questions-boundary {
  background: rgba(0, 243, 255, 0.03);
  border: 1px solid rgba(0, 243, 255, 0.22);
  border-left: 3px solid var(--neon-cyan);
  border-radius: 8px;
  padding: 0.9rem 1.2rem;
  margin: 1.25rem 0 1.75rem 0;
}

.care-questions-boundary-text {
  font: 400 0.88rem var(--font-body);
  color: var(--ink-secondary);
  line-height: 1.5;
  margin: 0;
}

.care-questions-boundary-text strong {
  color: var(--neon-cyan);
  font-weight: 600;
}

.care-questions-grid {
  display: grid;
  grid-template-columns: 1fr;
  gap: 1.25rem;
}

@media (min-width: 54rem) {
  .care-questions-grid {
    grid-template-columns: repeat(3, 1fr);
  }
}

.care-question-card {
  background: rgba(18, 20, 28, 0.75);
  border: 1px solid var(--border-glass);
  border-radius: 12px;
  padding: 1.35rem;
  display: flex;
  flex-direction: column;
  gap: 0.65rem;
  transition: border-color 0.2s ease, transform 0.2s ease;
}

.care-question-card:hover {
  border-color: rgba(167, 139, 250, 0.45);
  transform: translateY(-2px);
}

.care-question-num {
  font: 700 1.15rem var(--font-mono);
  color: #a78bfa;
  letter-spacing: 0.05em;
}

.care-question-heading {
  font-size: 1.05rem;
  font-weight: 600;
  color: var(--ink-primary);
  margin: 0;
  line-height: 1.35;
}

.care-question-prompt {
  font: 400 0.92rem var(--font-body);
  color: #e2e8f0;
  font-style: italic;
  margin: 0;
  line-height: 1.5;
  padding-left: 0.5rem;
  border-left: 2px solid rgba(167, 139, 250, 0.4);
}

.care-question-context {
  font: 400 0.82rem var(--font-body);
  color: var(--muted);
  margin: 0;
  line-height: 1.45;
}

#mucus-rheology-explorer,
#modifier-epistasis-explorer {
  margin-top: 3.5rem;
  margin-bottom: 3.5rem;
  background: rgba(12, 14, 20, 0.82);
  border: 1px solid var(--border-glass);
  border-radius: 14px;
  padding: 1.75rem;
}

.ptc-sim-header-row {
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  align-items: flex-start;
  gap: 0.85rem;
  margin-bottom: 0.6rem;
}

.ptc-sim-badges {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 0.5rem;
}

.badge-track-a {
  display: inline-block;
  margin-bottom: 0.45rem;
  color: var(--neon-cyan);
  background: rgba(0, 243, 255, 0.1);
  border: 1px solid rgba(0, 243, 255, 0.3);
  font: 600 0.72rem var(--font-mono);
  padding: 0.2rem 0.55rem;
  border-radius: 4px;
  text-transform: uppercase;
  letter-spacing: 0.05em;
}

.ptc-stage-badge {
  font: 600 0.72rem var(--font-mono);
  padding: 0.22rem 0.6rem;
  border-radius: 4px;
  letter-spacing: 0.03em;
  color: #00f3ff;
  background: rgba(0, 243, 255, 0.12);
  border: 1px solid rgba(0, 243, 255, 0.35);
}

.aso-controls-grid {
  display: grid;
  grid-template-columns: 1fr;
  gap: 1rem;
  margin: 1.25rem 0 1.5rem;
}

@media (min-width: 56rem) {
  .aso-controls-grid {
    grid-template-columns: repeat(3, 1fr);
  }
}

.aso-control-group {
  background: rgba(255, 255, 255, 0.025);
  border: 1px solid var(--border-glass);
  border-radius: 10px;
  padding: 1.1rem;
  display: flex;
  flex-direction: column;
  gap: 0.55rem;
}

.aso-control-label {
  display: flex;
  justify-content: space-between;
  align-items: baseline;
  gap: 0.5rem;
  font: 600 0.84rem var(--font-body);
  color: var(--ink-primary);
}

.aso-control-label strong {
  font: 700 0.95rem var(--font-mono);
  color: var(--neon-cyan);
}

.aso-control-hint {
  font: 400 0.76rem var(--font-body);
  color: var(--muted);
  margin: 0.15rem 0 0;
  line-height: 1.4;
}

.aso-readouts-grid {
  display: grid;
  grid-template-columns: 1fr;
  gap: 1rem;
  margin: 1.25rem 0;
}

@media (min-width: 40rem) {
  .aso-readouts-grid {
    grid-template-columns: repeat(2, 1fr);
  }
}

@media (min-width: 64rem) {
  .aso-readouts-grid {
    grid-template-columns: repeat(4, 1fr);
  }
}

.aso-metric-card {
  background: rgba(18, 22, 32, 0.85);
  border: 1px solid rgba(0, 243, 255, 0.2);
  border-radius: 10px;
  padding: 1.15rem;
  display: flex;
  flex-direction: column;
  justify-content: space-between;
  gap: 0.45rem;
}

.aso-metric-label {
  font: 600 0.74rem var(--font-mono);
  color: var(--ink-secondary);
  text-transform: uppercase;
  letter-spacing: 0.04em;
}

.aso-metric-val {
  font: 700 1.45rem var(--font-mono);
  color: var(--neon-cyan);
  line-height: 1.2;
}

.aso-metric-sub {
  font: 400 0.78rem var(--font-body);
  color: var(--muted);
  margin: 0;
  line-height: 1.35;
}

.ptc-badge-wrap {
  margin-top: 0.2rem;
}

.ptc-status-badge {
  display: inline-block;
  font: 600 0.7rem var(--font-mono);
  padding: 0.18rem 0.5rem;
  border-radius: 4px;
}

.ptc-status-badge.badge-danger {
  color: #ff6b6b;
  background: rgba(255, 107, 107, 0.14);
  border: 1px solid rgba(255, 107, 107, 0.35);
}

.ptc-status-badge.badge-warning {
  color: #ffd166;
  background: rgba(255, 209, 102, 0.14);
  border: 1px solid rgba(255, 209, 102, 0.35);
}

.ptc-status-badge.badge-success {
  color: #06d6a0;
  background: rgba(6, 214, 160, 0.14);
  border: 1px solid rgba(6, 214, 160, 0.35);
}

#endpoint-decoder {
  margin-top: 3.5rem;
  margin-bottom: 3.5rem;
}

.endpoint-tabs-list {
  display: grid;
  grid-template-columns: repeat(2, 1fr);
  gap: 0.6rem;
  margin: 1.25rem 0 1.5rem;
}

@media (min-width: 54rem) {
  .endpoint-tabs-list {
    grid-template-columns: repeat(4, 1fr);
  }
}

.endpoint-tab-btn {
  display: flex;
  align-items: center;
  gap: 0.6rem;
  padding: 0.75rem 1rem;
  min-height: 2.75rem;
  background: rgba(255, 255, 255, 0.03);
  border: 1px solid var(--border-glass);
  border-radius: 8px;
  color: var(--ink-secondary);
  font-family: var(--font-mono);
  font-size: 0.82rem;
  cursor: pointer;
  text-align: left;
  transition: border-color 0.2s ease, background 0.2s ease, color 0.2s ease;
}

.endpoint-tab-btn:hover {
  border-color: rgba(0, 243, 255, 0.4);
  color: var(--ink-primary);
}

.endpoint-tab-btn.active {
  background: rgba(0, 243, 255, 0.12);
  border-color: var(--neon-cyan);
  color: var(--ink-primary);
  font-weight: 600;
}

.endpoint-tab-btn .tab-indicator {
  font-weight: 700;
  color: var(--neon-cyan);
}

.endpoint-panel {
  background: rgba(18, 20, 28, 0.75);
  border: 1px solid var(--border-glass);
  border-radius: 12px;
  padding: 1.5rem;
  display: flex;
  flex-direction: column;
  gap: 1.25rem;
}

.endpoint-panel[hidden] {
  display: none;
}

.endpoint-card-header {
  display: flex;
  flex-direction: column;
  gap: 0.4rem;
}

.endpoint-badge {
  display: inline-block;
  align-self: flex-start;
  font: 600 0.72rem var(--font-mono);
  padding: 0.2rem 0.6rem;
  border-radius: 4px;
  text-transform: uppercase;
  letter-spacing: 0.04em;
}

.badge-fev1 {
  color: #00e5ff;
  background: rgba(0, 229, 255, 0.12);
  border: 1px solid rgba(0, 229, 255, 0.35);
}

.badge-sweat {
  color: #00e676;
  background: rgba(0, 230, 118, 0.12);
  border: 1px solid rgba(0, 230, 118, 0.35);
}

.badge-lci {
  color: #ffd700;
  background: rgba(255, 215, 0, 0.12);
  border: 1px solid rgba(255, 215, 0, 0.35);
}

.badge-cfqr {
  color: #b388ff;
  background: rgba(179, 136, 255, 0.12);
  border: 1px solid rgba(179, 136, 255, 0.35);
}

.endpoint-card-header h3 {
  font-size: 1.25rem;
  font-weight: 700;
  color: var(--ink-primary);
  margin: 0;
  line-height: 1.3;
}

.endpoint-detail-grid {
  display: grid;
  grid-template-columns: 1fr;
  gap: 1rem;
}

@media (min-width: 48rem) {
  .endpoint-detail-grid {
    grid-template-columns: repeat(2, 1fr);
  }
}

.endpoint-prop {
  background: rgba(255, 255, 255, 0.02);
  border: 1px solid rgba(255, 255, 255, 0.06);
  border-radius: 8px;
  padding: 1rem;
  display: flex;
  flex-direction: column;
  gap: 0.4rem;
}

.endpoint-prop.full-width {
  grid-column: 1 / -1;
}

.endpoint-prop-label {
  font: 600 0.78rem var(--font-mono);
  color: var(--neon-cyan);
  text-transform: uppercase;
  letter-spacing: 0.04em;
}

.endpoint-prop-val {
  font: 400 0.92rem var(--font-body);
  color: var(--ink-secondary);
  margin: 0;
  line-height: 1.5;
}

.endpoint-matrix-card {
  background: rgba(255, 255, 255, 0.03);
  border: 1px solid var(--border-glass);
  border-radius: 8px;
  padding: 1.25rem;
  margin-top: 1.5rem;
}

.endpoint-table-wrap {
  overflow-x: auto;
  margin-top: 0.85rem;
}

.endpoint-table {
  width: 100%;
  border-collapse: collapse;
  font-size: 0.88rem;
  font-family: var(--font-body);
}

.endpoint-table th,
.endpoint-table td {
  padding: 0.65rem 0.85rem;
  text-align: left;
  border-bottom: 1px solid rgba(255, 255, 255, 0.08);
}

.endpoint-table th {
  font-family: var(--font-mono);
  font-size: 0.78rem;
  color: var(--neon-cyan);
  text-transform: uppercase;
  letter-spacing: 0.04em;
}

.endpoint-table td {
  color: var(--ink-secondary);
}

.endpoint-table tbody tr:hover td {
  background: rgba(255, 255, 255, 0.02);
  color: var(--ink-primary);
}


.ptc-schematic-wrap {
  width: 100%;
  margin-block: 1.5rem;
  padding: 1rem;
  background: rgba(10, 15, 29, 0.78);
  border: 1px solid var(--border-glass, rgba(255, 255, 255, 0.1));
  border-radius: 12px;
  overflow-x: auto;
  box-shadow: 0 4px 20px rgba(0, 0, 0, 0.35);
  box-sizing: border-box;
}

.ptc-schematic-svg {
  display: block;
  width: 100%;
  height: auto;
  max-height: 240px;
}

.mucin-canvas-wrap {
  width: 100%;
  margin-block: 1.5rem;
  padding: 1.25rem;
  background: rgba(10, 15, 29, 0.85);
  border: 1px solid var(--border-glass, rgba(255, 255, 255, 0.1));
  border-radius: 12px;
  box-shadow: 0 4px 24px rgba(0, 0, 0, 0.4);
  box-sizing: border-box;
}

.mucin-canvas-header {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  justify-content: space-between;
  gap: 0.75rem;
  margin-bottom: 0.85rem;
}

.mucin-canvas-title {
  font: 600 0.92rem var(--font-body);
  color: var(--ink-primary);
  letter-spacing: 0.02em;
}

.mucin-canvas-actions {
  display: flex;
  align-items: center;
  gap: 0.5rem;
}

.mucin-mesh-canvas {
  display: block;
  width: 100%;
  max-width: 100%;
  aspect-ratio: 21 / 9;
  height: auto;
  background: #040814;
  border: 1px solid rgba(0, 243, 255, 0.15);
  border-radius: 8px;
}

@media (max-width: 1024px) {
  .mucin-mesh-canvas {
    aspect-ratio: 16 / 9;
  }
}

@media (max-width: 640px) {
  .mucin-mesh-canvas {
    aspect-ratio: 16 / 10;
    min-height: 180px;
  }
}

/* Animations for SVG Curves, Cilia, and Tree of Life Pulses */
@media (prefers-reduced-motion: no-preference) {
  .delivery-anim-path {
    stroke-dasharray: 1;
    stroke-dashoffset: 1;
    animation: delivery-draw-path 0.65s cubic-bezier(0.16, 1, 0.3, 1) forwards;
  }

  .aso-canonical-arc {
    stroke-dasharray: 8 5;
    animation: aso-flow-arc 2.4s linear infinite;
  }

  .cilia-beating {
    transform-origin: bottom center;
    animation: cilia-metachronal 1.8s ease-in-out infinite alternate;
  }

  .tol-branch-pulse {
    stroke-dasharray: 10 22;
    animation: tol-signal-flow 3.2s linear infinite;
  }

  .tol-core-halo {
    animation: tol-core-glow 4s ease-in-out infinite alternate;
  }
}

@keyframes delivery-draw-path {
  to {
    stroke-dashoffset: 0;
  }
}

@keyframes aso-flow-arc {
  to {
    stroke-dashoffset: -26;
  }
}

@keyframes cilia-metachronal {
  0% {
    transform: rotate(-10deg);
  }
  100% {
    transform: rotate(14deg);
  }
}

@keyframes tol-signal-flow {
  to {
    stroke-dashoffset: -32;
  }
}

@keyframes tol-core-glow {
  0% {
    transform: scale(1);
    opacity: 0.72;
  }
  100% {
    transform: scale(1.08);
    opacity: 1;
  }
}

@media (prefers-reduced-motion: reduce) {
  .delivery-anim-path {
    stroke-dasharray: none;
    stroke-dashoffset: 0;
    animation: none;
  }

  .aso-canonical-arc,
  .cilia-beating,
  .tol-branch-pulse,
  .tol-core-halo {
    animation: none;
  }
}

.is-anim-paused .cilia-beating,
.is-anim-paused .tol-branch-pulse,
.is-anim-paused .tol-core-halo,
.is-svg-paused .cilia-beating,
.is-svg-paused .tol-branch-pulse,
.is-svg-paused .tol-core-halo,
.is-svg-frozen-time .cilia-beating,
.is-svg-frozen-time .tol-branch-pulse,
.is-svg-frozen-time .tol-core-halo {
  animation-play-state: paused !important;
}

.tol-actions {
  display: flex;
  align-items: center;
  gap: 0.5rem;
  margin-top: 0.5rem;
}




/* --- Interactive Genotype-to-Modality Pathway Finder (T-0211) --- */
.genotype-pathway-card {
  margin-top: 2rem;
  margin-bottom: 2rem;
  background: rgba(12, 15, 22, 0.85);
  border: 1px solid rgba(255, 255, 255, 0.12);
  border-top: 3px solid var(--lime);
  border-radius: 12px;
  padding: 1.5rem;
  display: flex;
  flex-direction: column;
  gap: 1.25rem;
  max-width: 100%;
  box-sizing: border-box;
  overflow: hidden;
}

.pathway-header h3 {
  font-size: 1.22rem;
  font-weight: 600;
  color: var(--ink-primary);
  margin: 0.6rem 0 0.5rem;
  line-height: 1.3;
  overflow-wrap: anywhere;
}

.pathway-sub {
  font-size: 0.9rem;
  color: var(--ink-secondary);
  line-height: 1.55;
  margin: 0;
  overflow-wrap: anywhere;
}

.pathway-selector-block {
  background: rgba(255, 255, 255, 0.02);
  border: 1px solid rgba(255, 255, 255, 0.08);
  border-radius: 10px;
  padding: 1.1rem;
  display: flex;
  flex-direction: column;
  gap: 1rem;
}

.pathway-dim-label {
  display: block;
  font: 600 0.78rem var(--font-mono);
  color: var(--lime);
  text-transform: uppercase;
  letter-spacing: 0.04em;
  margin-bottom: 0.35rem;
}

.pathway-class-buttons {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
}

.pathway-class-btn {
  font: 500 0.82rem var(--font-mono);
  padding: 0.5rem 0.85rem;
  min-height: 44px;
  background: rgba(255, 255, 255, 0.04);
  border: 1px solid rgba(255, 255, 255, 0.14);
  border-radius: 6px;
  color: var(--ink-secondary);
  cursor: pointer;
  display: inline-flex;
  align-items: center;
  justify-content: center;
  transition: all 0.15s ease;
}

.pathway-class-btn:hover {
  background: rgba(255, 255, 255, 0.08);
  border-color: rgba(255, 255, 255, 0.28);
  color: var(--ink-primary);
}

.pathway-class-btn.active {
  background: rgba(163, 230, 53, 0.15);
  border-color: var(--lime);
  color: var(--lime);
  font-weight: 600;
}

.pathway-preset-control {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 0.75rem;
}

.pathway-preset-label {
  font: 500 0.82rem var(--font-mono);
  color: var(--ink-secondary);
}

.pathway-select {
  background: #0d1117;
  border: 1px solid rgba(255, 255, 255, 0.18);
  border-radius: 6px;
  color: var(--ink-primary);
  font: 0.85rem var(--font-mono);
  padding: 0.45rem 0.75rem;
  min-height: 44px;
  cursor: pointer;
}

.pathway-grid {
  display: grid;
  grid-template-columns: 1fr;
  gap: 1rem;
}

@media (min-width: 840px) {
  .pathway-grid {
    grid-template-columns: 1fr 1fr;
  }
}

.pathway-block {
  background: rgba(255, 255, 255, 0.02);
  border: 1px solid rgba(255, 255, 255, 0.08);
  border-radius: 10px;
  padding: 1.1rem;
  display: flex;
  flex-direction: column;
  gap: 0.75rem;
}

.pathway-badge-wrap {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 0.5rem;
  flex-wrap: wrap;
}

.pathway-badge {
  font: 600 0.72rem var(--font-mono);
  padding: 0.2rem 0.55rem;
  border-radius: 4px;
  text-transform: uppercase;
  letter-spacing: 0.04em;
}

.pathway-badge.badge-approved {
  background: rgba(34, 197, 94, 0.15);
  border: 1px solid rgba(34, 197, 94, 0.4);
  color: #4ade80;
}

.pathway-badge.badge-ineligible {
  background: rgba(239, 68, 68, 0.15);
  border: 1px solid rgba(239, 68, 68, 0.4);
  color: #f87171;
}

.pathway-badge.badge-conditional {
  background: rgba(234, 179, 8, 0.15);
  border: 1px solid rgba(234, 179, 8, 0.4);
  color: #facc15;
}

.pathway-desc {
  font-size: 0.88rem;
  color: var(--ink-primary);
  line-height: 1.55;
  margin: 0;
}

.pathway-meta-line {
  font-size: 0.82rem;
  color: var(--ink-secondary);
  line-height: 1.5;
  margin: 0;
}

.pathway-k {
  font: 600 0.76rem var(--font-mono);
  color: var(--lime);
  text-transform: uppercase;
  letter-spacing: 0.03em;
  display: inline-block;
  margin-right: 0.25rem;
}

.pathway-list {
  margin: 0;
  padding-left: 1.25rem;
  font-size: 0.85rem;
  color: var(--ink-secondary);
  line-height: 1.5;
}

.pathway-list li {
  margin-bottom: 0.35rem;
}

.pathway-trials-container {
  display: flex;
  flex-direction: column;
  gap: 0.75rem;
}

.pathway-trial-card {
  background: rgba(0, 0, 0, 0.3);
  border: 1px solid rgba(255, 255, 255, 0.08);
  border-radius: 8px;
  padding: 0.85rem;
  display: flex;
  flex-direction: column;
  gap: 0.4rem;
}

.pathway-trial-header {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 0.5rem;
  flex-wrap: wrap;
}

.pathway-nct-link {
  font: 600 0.85rem var(--font-mono);
  color: var(--lime);
  text-decoration: none;
  min-height: 44px;
  display: inline-flex;
  align-items: center;
}

.pathway-nct-link:hover {
  text-decoration: underline;
}

.pathway-trial-phase {
  font: 500 0.72rem var(--font-mono);
  color: var(--ink-secondary);
  background: rgba(255, 255, 255, 0.06);
  padding: 0.15rem 0.45rem;
  border-radius: 4px;
}

.pathway-trial-title {
  font-size: 0.85rem;
  color: var(--ink-primary);
  line-height: 1.35;
}

.pathway-trial-modality {
  font-size: 0.82rem;
  color: var(--ink-secondary);
  margin: 0;
}

.pathway-trial-mech {
  font-size: 0.8rem;
  color: var(--ink-secondary);
  line-height: 1.45;
  margin: 0;
}

.pathway-care-box {
  background: rgba(163, 230, 53, 0.03);
  border: 1px solid rgba(163, 230, 53, 0.18);
  border-radius: 8px;
  padding: 0.85rem;
}

.pathway-care-text {
  font-size: 0.85rem;
  color: var(--ink-primary);
  line-height: 1.5;
  margin: 0;
}

.pathway-disclaimer-box {
  background: rgba(0, 0, 0, 0.4);
  border: 1px solid rgba(255, 255, 255, 0.08);
  border-radius: 8px;
  padding: 0.85rem;
  font-size: 0.8rem;
  color: var(--ink-secondary);
  line-height: 1.45;
}

@media (prefers-reduced-motion: reduce) {
  .pathway-class-btn {
    transition: none !important;
  }
}

/* ==========================================================================
   CFTR Functional Variant Classes (Class I–VII) Genetics Primer (T-0212)
   ========================================================================== */

.variant-classes-wrap,
.cf-classes-root {
  margin-top: 1.5rem;
  margin-bottom: 2.5rem;
  display: flex;
  flex-direction: column;
  gap: 1.25rem;
}

.cf-classes-intro-card {
  background: rgba(12, 15, 22, 0.85);
  border: 1px solid rgba(255, 255, 255, 0.12);
  border-left: 3px solid var(--neon-cyan);
  border-radius: 12px;
  padding: 1.25rem 1.4rem;
  display: flex;
  flex-direction: column;
  gap: 0.75rem;
  box-shadow: 0 4px 20px rgba(0, 0, 0, 0.35);
}

.cf-classes-intro-text {
  font-size: 0.92rem;
  line-height: 1.6;
  color: var(--ink-secondary);
  margin: 0;
}

.cf-classes-boundary {
  background: rgba(0, 243, 255, 0.04);
  border: 1px solid rgba(0, 243, 255, 0.2);
  border-radius: 8px;
  padding: 0.8rem 1rem;
}

.cf-classes-boundary-text {
  font: 500 0.82rem var(--font-mono);
  color: var(--neon-cyan);
  line-height: 1.45;
  margin: 0;
}

.cf-classes-toolbar {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  justify-content: space-between;
  gap: 0.75rem;
  margin: 0.5rem 0;
}

.classes-filter-bar,
.cf-classes-filter-bar {
  display: flex;
  flex-wrap: wrap;
  gap: 0.45rem;
}

.class-filter-btn,
.cf-classes-filter-btn {
  font: 500 0.8rem var(--font-mono);
  padding: 0.45rem 0.8rem;
  min-height: 38px;
  background: rgba(255, 255, 255, 0.04);
  border: 1px solid rgba(255, 255, 255, 0.14);
  border-radius: 6px;
  color: var(--ink-secondary);
  cursor: pointer;
  display: inline-flex;
  align-items: center;
  justify-content: center;
  transition: all 0.15s ease;
}

.cf-classes-filter-btn:hover {
  background: rgba(255, 255, 255, 0.08);
  border-color: rgba(0, 243, 255, 0.35);
  color: var(--ink-primary);
}

.cf-classes-filter-btn.active {
  background: rgba(0, 243, 255, 0.15);
  border-color: var(--neon-cyan);
  color: var(--neon-cyan);
  font-weight: 600;
}

.cf-classes-anim-btn {
  font: 500 0.74rem var(--font-mono);
  padding: 0.35rem 0.75rem;
  min-height: 28px;
  background: rgba(255, 255, 255, 0.04);
  border: 1px solid rgba(255, 255, 255, 0.16);
  border-radius: 6px;
  color: var(--ink-secondary);
  cursor: pointer;
  display: inline-flex;
  align-items: center;
  transition: all 0.15s ease;
}

.cf-classes-anim-btn:hover {
  border-color: var(--neon-cyan);
  color: var(--neon-cyan);
}

/* Schematic SVG Stage */
.cf-lifecycle-svg-stage {
  margin-block: 1.25rem;
  padding: 1.15rem;
  background: rgba(10, 15, 29, 0.88);
  border: 1px solid var(--border-glass, rgba(255, 255, 255, 0.1));
  border-radius: 12px;
  overflow-x: auto;
  box-shadow: 0 4px 24px rgba(0, 0, 0, 0.4);
}

.cf-lifecycle-svg-container {
  width: 100%;
}

.cftr-class-lifecycle-svg {
  display: block;
  width: 100%;
  min-width: 780px;
  height: auto;
}

/* Compartments */
.cf-comp-rect {
  fill: rgba(14, 21, 36, 0.65);
  stroke: rgba(255, 255, 255, 0.12);
  stroke-width: 1.2;
  transition: all 0.2s ease;
}

.cf-comp-title {
  font-family: var(--font-mono);
  font-size: 10px;
  font-weight: 700;
  fill: var(--neon-cyan);
  letter-spacing: 0.05em;
}

.cf-comp-sub {
  font-family: var(--font-mono);
  font-size: 8.5px;
  fill: var(--muted);
}

.cf-comp-group.is-comp-active .cf-comp-rect {
  stroke: rgba(0, 243, 255, 0.45);
  fill: rgba(14, 21, 36, 0.92);
}

.cf-comp-group.is-comp-dimmed .cf-comp-rect {
  opacity: 0.4;
}

/* Trajectories */
.cf-lifecycle-path {
  fill: none;
  stroke: rgba(0, 243, 255, 0.35);
  stroke-width: 2;
  stroke-dasharray: 6 4;
  animation: cftrDashMarch 2.2s linear infinite;
}

.cf-lifecycle-path.cf-path-efflux {
  stroke: #00e676;
  stroke-width: 2.2;
}

@keyframes cftrDashMarch {
  to {
    stroke-dashoffset: -20;
  }
}

/* Pulses */
.cf-lifecycle-pulse {
  fill: #00f3ff;
  filter: drop-shadow(0 0 5px #00f3ff);
  animation: cftrPulseGlide 2.8s ease-in-out infinite alternate;
}

.cf-lifecycle-pulse.pulse-efflux {
  fill: #00e676;
  filter: drop-shadow(0 0 5px #00e676);
}

@keyframes cftrPulseGlide {
  0% {
    transform: scale(0.9);
    opacity: 0.65;
  }
  100% {
    transform: scale(1.15);
    opacity: 1;
  }
}

/* Checkpoint Nodes */
.cf-checkpoint-node {
  cursor: pointer;
  outline: none;
}

.cf-node-ring {
  fill: rgba(14, 21, 36, 0.85);
  stroke: rgba(255, 255, 255, 0.22);
  stroke-width: 1.5;
  transition: all 0.2s ease;
}

.cf-node-core {
  fill: var(--neon-cyan);
  transition: all 0.2s ease;
}

.cf-node-label {
  font-family: var(--font-mono);
  font-size: 9.5px;
  font-weight: 600;
  fill: var(--ink-primary);
}

.cf-node-sub {
  font-family: var(--font-mono);
  font-size: 8px;
  fill: var(--muted);
}

.cf-checkpoint-node:hover .cf-node-ring,
.cf-checkpoint-node:focus-visible .cf-node-ring {
  stroke: var(--neon-cyan);
  stroke-width: 2.5;
}

.cf-checkpoint-node.is-active .cf-node-ring {
  stroke: var(--neon-cyan);
  stroke-width: 3;
  fill: rgba(0, 243, 255, 0.15);
}

.cf-checkpoint-node.is-active .cf-node-core {
  fill: #a8ff60;
}

.cf-checkpoint-node.is-dimmed {
  opacity: 0.35;
}

/* Paused Animation State */
.cf-lifecycle-svg-container.is-anim-paused .cf-lifecycle-path,
.cf-lifecycle-svg-container.is-anim-paused .cf-lifecycle-pulse {
  animation-play-state: paused !important;
}

/* Seven Primer Cards Grid */
.classes-grid,
.cf-classes-cards-grid {
  display: grid;
  grid-template-columns: 1fr;
  gap: 1.25rem;
  margin-top: 1rem;
}

@media (min-width: 52rem) {
  .classes-grid,
  .cf-classes-cards-grid {
    grid-template-columns: repeat(2, 1fr);
  }
}

@media (min-width: 76rem) {
  .classes-grid,
  .cf-classes-cards-grid {
    grid-template-columns: repeat(3, 1fr);
  }
}

.class-card,
.cf-class-card {
  background: rgba(14, 21, 36, 0.78);
  border: 1px solid var(--border-glass, rgba(255, 255, 255, 0.1));
  border-radius: 12px;
  padding: 1.25rem;
  display: flex;
  flex-direction: column;
  gap: 0.75rem;
  box-shadow: 0 4px 16px rgba(0, 0, 0, 0.3);
  transition: border-color 0.2s ease, transform 0.2s ease;
}

.class-card:hover,
.cf-class-card:hover {
  border-color: rgba(0, 243, 255, 0.4);
  transform: translateY(-2px);
}

.cf-class-card[hidden] {
  display: none !important;
}

.cf-card-header {
  display: flex;
  flex-direction: column;
  gap: 0.4rem;
}

.cf-card-badge-wrap {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 0.5rem;
  flex-wrap: wrap;
}

.cf-card-code {
  font: 700 0.82rem var(--font-mono);
  color: var(--neon-cyan);
  text-transform: uppercase;
  letter-spacing: 0.05em;
}

.cf-card-status {
  font: 600 0.7rem var(--font-mono);
  padding: 0.15rem 0.5rem;
  border-radius: 4px;
  letter-spacing: 0.03em;
}

.cf-card-status.badge-approved {
  background: rgba(34, 197, 94, 0.15);
  border: 1px solid rgba(34, 197, 94, 0.4);
  color: #4ade80;
}

.cf-card-status.badge-investigational {
  background: rgba(0, 243, 255, 0.12);
  border: 1px solid rgba(0, 243, 255, 0.35);
  color: #00f3ff;
}

.cf-card-title {
  font-size: 1.05rem;
  font-weight: 700;
  color: var(--ink-primary);
  margin: 0;
  line-height: 1.35;
}

.cf-card-archetype-row {
  font-size: 0.82rem;
  color: var(--ink-secondary);
  line-height: 1.45;
}

.cf-card-archetype-row .cf-k {
  font: 600 0.74rem var(--font-mono);
  color: var(--lime);
  text-transform: uppercase;
}

.cf-card-archetype-row .cf-v {
  color: var(--ink-primary);
}

.cf-card-box {
  background: rgba(255, 255, 255, 0.025);
  border: 1px solid rgba(255, 255, 255, 0.07);
  border-radius: 8px;
  padding: 0.85rem;
  display: flex;
  flex-direction: column;
  gap: 0.35rem;
}

.cf-box-title {
  font: 600 0.74rem var(--font-mono);
  text-transform: uppercase;
  letter-spacing: 0.03em;
  color: var(--neon-cyan);
  margin: 0;
}

.cf-box-text {
  font-size: 0.84rem;
  color: var(--ink-secondary);
  margin: 0;
  line-height: 1.5;
}

.cf-card-link-wrap {
  margin-top: auto;
  padding-top: 0.4rem;
}

.cf-companion-link {
  font: 600 0.82rem var(--font-mono);
  color: var(--neon-cyan);
  text-decoration: none;
  display: inline-flex;
  align-items: center;
  min-height: 36px;
}

.cf-companion-link:hover {
  text-decoration: underline;
}

/* Counselor Questions Panel & Dignity Boundary */
.classes-counselor-panel {
  background: rgba(163, 230, 53, 0.04);
  border: 1px solid rgba(163, 230, 53, 0.22);
  border-radius: 10px;
  padding: 1.25rem;
  display: flex;
  flex-direction: column;
  gap: 0.85rem;
  margin-top: 1rem;
}

.counselor-panel-title {
  font-size: 1.05rem;
  font-weight: 600;
  color: var(--lime);
  margin: 0;
}

.counselor-panel-sub {
  font-size: 0.86rem;
  color: var(--ink-secondary);
  margin: 0;
  line-height: 1.45;
}

.counselor-questions-grid {
  display: grid;
  grid-template-columns: 1fr;
  gap: 0.85rem;
}

@media (min-width: 768px) {
  .counselor-questions-grid {
    grid-template-columns: 1fr 1fr;
  }
}

.counselor-q-item {
  background: rgba(0, 0, 0, 0.35);
  border: 1px solid rgba(255, 255, 255, 0.07);
  border-left: 3px solid var(--lime);
  border-radius: 6px;
  padding: 0.75rem 0.9rem;
  display: flex;
  flex-direction: column;
  gap: 0.35rem;
}

.counselor-q-title {
  font-size: 0.86rem;
  font-weight: 600;
  color: var(--ink-primary);
  margin: 0;
  line-height: 1.4;
}

.counselor-q-note {
  font-size: 0.8rem;
  color: var(--ink-secondary);
  margin: 0;
  line-height: 1.45;
}

.cf-classes-disclaimer {
  font-size: 0.82rem;
  line-height: 1.5;
  color: var(--muted);
  margin-top: 0.5rem;
}

/* ==========================================================================
   Decision Flow Schematic SVG Stage (/cf/registries/)
   ========================================================================== */

.pathway-flow-stage {
  margin-block: 1.25rem;
  padding: 1rem;
  background: rgba(10, 15, 29, 0.82);
  border: 1px solid var(--border-glass, rgba(255, 255, 255, 0.1));
  border-radius: 12px;
  overflow-x: auto;
  box-shadow: 0 4px 20px rgba(0, 0, 0, 0.35);
}

.pathway-flow-bar {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 0.75rem;
  margin-bottom: 0.65rem;
  flex-wrap: wrap;
}

.pathway-anim-btn {
  font: 500 0.74rem var(--font-mono);
  padding: 0.3rem 0.7rem;
  min-height: 28px;
  background: rgba(255, 255, 255, 0.04);
  border: 1px solid rgba(255, 255, 255, 0.16);
  border-radius: 6px;
  color: var(--ink-secondary);
  cursor: pointer;
  display: inline-flex;
  align-items: center;
  transition: all 0.15s ease;
}

.pathway-anim-btn:hover {
  border-color: var(--lime);
  color: var(--lime);
}

.pathway-flow-svg {
  display: block;
  width: 100%;
  min-width: 760px;
  height: auto;
}

/* Pathway Decision Flow Nodes & Edges */
.pflow-node-rect {
  fill: rgba(14, 21, 36, 0.85);
  stroke: rgba(255, 255, 255, 0.14);
  stroke-width: 1.2;
  transition: all 0.2s ease;
}

.pflow-node-rect.active-cyan {
  stroke: var(--neon-cyan);
  stroke-width: 2;
  fill: rgba(0, 243, 255, 0.1);
}

.pflow-node-rect.active-lime {
  stroke: var(--lime);
  stroke-width: 2;
  fill: rgba(163, 230, 53, 0.1);
}

.pflow-node-rect.active-rose {
  stroke: #ff6b8b;
  stroke-width: 2;
  fill: rgba(255, 107, 139, 0.1);
}

.pflow-node-rect.node-approved {
  stroke: #4ade80;
  stroke-width: 2;
  fill: rgba(34, 197, 94, 0.1);
}

.pflow-node-rect.node-conditional {
  stroke: #facc15;
  stroke-width: 2;
  fill: rgba(234, 179, 8, 0.1);
}

.pflow-node-rect.node-danger {
  stroke: #f87171;
  stroke-width: 2;
  fill: rgba(239, 68, 68, 0.1);
}

.pflow-node-rect.node-dimmed {
  opacity: 0.4;
}

.pflow-node-kicker {
  font-family: var(--font-mono);
  font-size: 8.5px;
  font-weight: 700;
  fill: var(--lime);
  letter-spacing: 0.05em;
}

.pflow-node-title {
  font-family: var(--font-display, "Space Grotesk", sans-serif);
  font-size: 11px;
  font-weight: 700;
  fill: var(--ink-primary);
}

.pflow-node-sub {
  font-family: var(--font-mono);
  font-size: 8.5px;
  fill: var(--muted);
}

.pflow-node-badge {
  font-family: var(--font-mono);
  font-size: 8px;
  font-weight: 600;
  fill: var(--neon-cyan);
  letter-spacing: 0.04em;
}

.pathway-edge {
  fill: none;
  stroke: rgba(255, 255, 255, 0.16);
  stroke-width: 1.5;
  stroke-dasharray: 4 4;
}

.pathway-edge.pathway-edge-active {
  stroke-dasharray: 6 4;
  animation: pathwayDashMarch 2s linear infinite;
}

.pathway-edge.edge-cyan {
  stroke: var(--neon-cyan);
  stroke-width: 2.4;
}

.pathway-edge.edge-lime {
  stroke: var(--lime);
  stroke-width: 2.4;
}

.pathway-edge.edge-rose {
  stroke: #ff6b8b;
  stroke-width: 2.4;
}

.pathway-edge.edge-inactive {
  opacity: 0.25;
}

@keyframes pathwayDashMarch {
  to {
    stroke-dashoffset: -20;
  }
}

.pathway-pulse {
  fill: var(--neon-cyan);
  filter: drop-shadow(0 0 5px var(--neon-cyan));
  animation: pathwayPulseGlow 2.5s ease-in-out infinite alternate;
}

.pathway-pulse.pulse-top {
  fill: var(--lime);
  filter: drop-shadow(0 0 5px var(--lime));
}

.pathway-pulse.pulse-bottom {
  fill: #ff6b8b;
  filter: drop-shadow(0 0 5px #ff6b8b);
}

@keyframes pathwayPulseGlow {
  0% {
    transform: scale(0.85);
    opacity: 0.6;
  }
  100% {
    transform: scale(1.15);
    opacity: 1;
  }
}

.pathway-flow-svg.is-anim-paused .pathway-edge.pathway-edge-active,
.pathway-flow-svg.is-anim-paused .pathway-pulse {
  animation-play-state: paused !important;
}

@media (prefers-reduced-motion: reduce) {
  .cf-lifecycle-path,
  .cf-lifecycle-pulse,
  .pathway-edge.pathway-edge-active,
  .pathway-pulse {
    animation: none !important;
    transition: none !important;
  }
}

/* --- WebGL2 Ciliary Escalator & Base Editing / ace-tRNA Workbench (Wave 9) --- */
.asl-cilia-schematic-box {
  display: flex;
  flex-direction: column;
  gap: 0.75rem;
  width: 100%;
}

.asl-cilia-gl-canvas {
  width: 100%;
  max-width: 100%;
  aspect-ratio: 21 / 9;
  height: auto;
  min-height: 170px;
  border-radius: 8px;
  background: #060a14;
  border: 1px solid rgba(0, 243, 255, 0.2);
  display: block;
}

@media (max-width: 1024px) {
  .asl-cilia-gl-canvas {
    aspect-ratio: 16 / 9;
  }
}

@media (max-width: 640px) {
  .asl-cilia-gl-canvas {
    aspect-ratio: 16 / 10;
    min-height: 160px;
  }
}

.asl-cilia-svg-wrap {
  width: 100%;
}

.abe8e-window-svg {
  width: 100%;
  max-width: 100%;
  height: auto;
  border-radius: 8px;
  background: #060a14;
  border: 1px solid rgba(0, 243, 255, 0.2);
  display: block;
}

@media (prefers-reduced-motion: no-preference) {
  .abe8e-gaussian-curve {
    animation: abe8e-pulse 2.8s ease-in-out infinite alternate;
  }
}

@keyframes abe8e-pulse {
  0% {
    stroke-opacity: 0.85;
  }
  100% {
    stroke-opacity: 1;
    filter: drop-shadow(0 0 4px rgba(0, 243, 255, 0.6));
  }
}

.is-anim-paused .abe8e-gaussian-curve,
.is-svg-paused .abe8e-gaussian-curve,
.is-svg-frozen-time .abe8e-gaussian-curve {
  animation-play-state: paused !important;
}

@media (prefers-reduced-motion: reduce) {
  .abe8e-gaussian-curve {
    animation: none !important;
  }
}

/* --- Persona Compass Bar (Home) & Workbench Discipline Filter Bar (/cf/delivery/, /cf/cftr/) --- */
.track-card[hidden],
section[data-discipline][hidden] {
  display: none !important;
}
.persona-compass-bar,
.workbench-discipline-bar {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 0.55rem;
  margin: 1rem 0 1.25rem;
  padding: 0.75rem 1rem;
  background: rgba(8, 15, 28, 0.78);
  border: 1px solid rgba(0, 243, 255, 0.24);
  border-radius: 10px;
}
.workbench-discipline-head {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  justify-content: space-between;
  width: 100%;
  gap: 0.5rem;
}
.workbench-discipline-kicker {
  font-family: var(--font-mono, monospace);
  font-size: 0.78rem;
  letter-spacing: 0.04em;
  text-transform: uppercase;
  color: rgba(226, 232, 240, 0.85);
  margin-right: 0.35rem;
}
.workbench-discipline-pills,
.workbench-discipline-btns {
  display: flex;
  flex-wrap: wrap;
  gap: 0.45rem;
}
.persona-filter-btn,
.discipline-filter-btn {
  appearance: none;
  background: rgba(15, 23, 42, 0.85);
  color: rgba(226, 232, 240, 0.92);
  border: 1px solid rgba(148, 163, 184, 0.32);
  border-radius: 999px;
  padding: 0.42rem 0.85rem;
  min-height: 2.75rem;
  font-family: var(--font-mono, monospace);
  font-size: 0.78rem;
  line-height: 1.2;
  cursor: pointer;
  transition: border-color 0.15s ease, background-color 0.15s ease, color 0.15s ease;
}
.persona-filter-btn:hover,
.discipline-filter-btn:hover {
  border-color: rgba(0, 243, 255, 0.65);
  color: #ffffff;
}
.persona-filter-btn.is-active,
.discipline-filter-btn.is-active {
  background: rgba(0, 243, 255, 0.16);
  border-color: #00f3ff;
  color: #ffffff;
  font-weight: 600;
}
.persona-filter-btn:focus-visible,
.discipline-filter-btn:focus-visible {
  outline: 2px solid #00f3ff;
  outline-offset: 2px;
  border-color: #00f3ff;
  color: #ffffff;
}
.workbench-discipline-status {
  font-family: var(--font-mono, monospace);
  font-size: 0.76rem;
  color: rgba(148, 163, 184, 0.92);
}

/* --- Cross-Scale Workbench Bridge Cards --- */
.workbench-cross-scale-bridge {
  margin-top: 1rem;
  padding-top: 0.85rem;
  border-top: 1px solid rgba(0, 243, 255, 0.18);
  display: flex;
  flex-direction: column;
  gap: 0.75rem;
}

.workbench-cross-scale-header {
  display: flex;
  flex-direction: column;
  gap: 0.35rem;
}

.workbench-cross-scale-title {
  font-size: 1.05rem;
  font-weight: 600;
  color: #e4eefb;
  margin: 0;
  line-height: 1.35;
}

.workbench-cross-scale-desc {
  font-size: 0.86rem;
  color: #94a3b8;
  margin: 0;
  line-height: 1.45;
}

.workbench-cross-scale-cards {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
  gap: 0.75rem;
  margin-top: 0.35rem;
}

.cross-scale-card {
  display: flex;
  flex-direction: column;
  gap: 0.5rem;
  padding: 0.85rem 1rem;
  border-radius: 8px;
  background: rgba(15, 23, 42, 0.75);
  border: 1px solid rgba(148, 163, 184, 0.22);
  transition: border-color 0.15s ease, background-color 0.15s ease;
}

.cross-scale-card:hover {
  border-color: rgba(0, 243, 255, 0.45);
  background: rgba(15, 23, 42, 0.9);
}

.cross-scale-card[hidden] {
  display: none !important;
}

.cross-scale-card-head {
  display: flex;
  flex-direction: column;
  gap: 0.2rem;
}

.cross-scale-tag {
  font-family: var(--font-mono, monospace);
  font-size: 0.72rem;
  letter-spacing: 0.04em;
  text-transform: uppercase;
  color: #7ee8fa;
}

.cross-scale-card-head h3,
.cross-scale-card-head h4 {
  font-size: 0.95rem;
  font-weight: 600;
  color: #f1f5f9;
  margin: 0;
  line-height: 1.3;
}

.cross-scale-card p {
  font-size: 0.84rem;
  color: #cbd5e1;
  margin: 0;
  line-height: 1.45;
  flex-grow: 1;
}

.cross-scale-meta-row {
  display: flex;
  flex-direction: column;
  gap: 0.35rem;
  padding-top: 0.5rem;
  border-top: 1px solid rgba(255, 255, 255, 0.08);
  font-size: 0.8rem;
  color: #94a3b8;
}

.cross-scale-meta-item strong {
  color: #e2e8f0;
}

.cross-scale-link {
  color: #00f3ff;
  text-decoration: underline;
  text-underline-offset: 2px;
}

.cross-scale-link:hover {
  color: #38bdf8;
}

.cross-scale-cta-row {
  padding-top: 0.4rem;
}

.cross-scale-cta-btn {
  display: inline-flex;
  align-items: center;
  min-height: 2.75rem;
  padding: 0.45rem 0.85rem;
  font-family: var(--font-mono, monospace);
  font-size: 0.78rem;
  font-weight: 500;
  color: #00f3ff;
  background: rgba(0, 243, 255, 0.08);
  border: 1px solid rgba(0, 243, 255, 0.32);
  border-radius: 6px;
  text-decoration: none;
  transition: background-color 0.15s ease, border-color 0.15s ease;
}

.cross-scale-cta-btn:hover {
  background: rgba(0, 243, 255, 0.18);
  border-color: #00f3ff;
  color: #ffffff;
}

/* ==========================================================================
   2025/2026 Zero-Build Web Standards & Adaptive Persona Command Deck
   ========================================================================== */

@media (prefers-reduced-motion: no-preference) {
  @view-transition {
    navigation: auto;
  }
}

/* Offscreen layout/paint containment for multi-simulator workbenches */
main section.aso-section,
main article.workbench-submodule {
  content-visibility: auto;
  contain-intrinsic-size: auto 560px;
}

.workbench-submodule {
  margin-top: 2rem;
  padding-top: 1.75rem;
  border-top: 1px dashed rgba(0, 243, 255, 0.24);
}

.persona-command-deck {
  container-type: inline-size;
  margin: 0 0 1.35rem;
  padding: 1rem 1.25rem;
  border-radius: 10px;
  background: linear-gradient(135deg, rgba(10, 18, 32, 0.92), rgba(15, 23, 42, 0.85));
  border: 1px solid rgba(0, 243, 255, 0.28);
  box-shadow: 0 6px 24px rgba(0, 0, 0, 0.32);
}

.persona-deck-panel[hidden] {
  display: none !important;
}

.persona-deck-panel:not([hidden]) {
  display: flex;
  flex-direction: column;
  gap: 0.85rem;
  opacity: 1;
  transform: translateY(0);
  transition: opacity 0.18s ease, transform 0.18s ease;
}

@starting-style {
  .persona-deck-panel:not([hidden]) {
    opacity: 0;
    transform: translateY(4px);
  }
}

.persona-deck-header {
  display: flex;
  flex-direction: column;
  gap: 0.25rem;
}

.persona-deck-tag {
  font-family: var(--font-mono, monospace);
  font-size: 0.74rem;
  font-weight: 600;
  text-transform: uppercase;
  letter-spacing: 0.05em;
  color: #00f3ff;
}

.persona-deck-desc {
  margin: 0;
  font-size: 0.88rem;
  line-height: 1.5;
  color: #cbd5e1;
}

.persona-deck-links {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(220px, 1fr));
  gap: 0.6rem;
}

@container (max-width: 560px) {
  .persona-deck-links {
    grid-template-columns: 1fr;
  }
}

.persona-deck-link {
  display: inline-flex;
  align-items: center;
  justify-content: space-between;
  min-height: 44px;
  padding: 0.5rem 0.85rem;
  border-radius: 7px;
  background: rgba(255, 255, 255, 0.04);
  border: 1px solid rgba(148, 163, 184, 0.24);
  color: #f1f5f9;
  font-family: var(--font-mono, monospace);
  font-size: 0.8rem;
  font-weight: 500;
  text-decoration: none;
  transition: background-color 0.15s ease, border-color 0.15s ease, color 0.15s ease;
}

.persona-deck-link:hover,
.persona-deck-link:focus-visible {
  background: rgba(0, 243, 255, 0.12);
  border-color: #00f3ff;
  color: #ffffff;
}

.persona-compass-prefix {
  font-family: var(--font-mono, monospace);
  font-size: 0.74rem;
  font-weight: 600;
  letter-spacing: 0.05em;
  text-transform: uppercase;
  color: #7ee8fa;
  margin-right: 0.25rem;
}

.persona-compass-status-bar {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  justify-content: space-between;
  width: 100%;
  gap: 0.5rem;
  padding-top: 0.45rem;
  margin-top: 0.15rem;
  border-top: 1px solid rgba(0, 243, 255, 0.18);
}

.persona-compass-status-text {
  font-family: var(--font-mono, monospace);
  font-size: 0.76rem;
  color: #cbd5e1;
}

.persona-reset-chip {
  appearance: none;
  background: rgba(0, 243, 255, 0.12);
  color: #00f3ff;
  border: 1px solid rgba(0, 243, 255, 0.4);
  border-radius: 999px;
  padding: 0.28rem 0.75rem;
  min-height: 2rem;
  font-family: var(--font-mono, monospace);
  font-size: 0.74rem;
  font-weight: 600;
  cursor: pointer;
  transition: background-color 0.15s ease, border-color 0.15s ease, color 0.15s ease;
}

.persona-reset-chip:hover,
.persona-reset-chip:focus-visible {
  background: rgba(0, 243, 255, 0.24);
  border-color: #00f3ff;
  color: #ffffff;
}

main [data-persona-scope].is-persona-dimmed,
main section.is-persona-dimmed {
  opacity: 0.52;
  filter: saturate(0.65);
  transition: opacity 0.22s ease, filter 0.22s ease;
}

main [data-persona-scope].is-persona-dimmed:hover,
main [data-persona-scope].is-persona-dimmed:focus-within,
main section.is-persona-dimmed:hover,
main section.is-persona-dimmed:focus-within {
  opacity: 1;
  filter: none;
}

.discipline-compact-btn {
  display: inline-flex;
  align-items: center;
  min-height: 44px;
  padding: 0.4rem 0.85rem;
  margin-left: auto;
  border-radius: 6px;
  background: rgba(255, 255, 255, 0.05);
  border: 1px solid rgba(0, 243, 255, 0.32);
  color: #e2e8f0;
  font-family: var(--font-mono, monospace);
  font-size: 0.78rem;
  font-weight: 600;
  cursor: pointer;
}

.discipline-compact-btn:hover,
.discipline-compact-btn.is-active {
  background: rgba(0, 243, 255, 0.16);
  border-color: #00f3ff;
  color: #ffffff;
}

main.is-workbench-compact .aso-controls-grid,
main.is-workbench-compact .aso-controls-panel,
main.is-workbench-compact .ptc-sim-canvas-wrap,
main.is-workbench-compact .aso-canvas-wrap,
main.is-workbench-compact .aso-visualizer-container,
main.is-workbench-compact .aso-defect-summary-card,
main.is-workbench-compact .evidence-card,
main.is-workbench-compact .nbd1-controls-row,
main.is-workbench-compact .nbd1-viz-wrap,
main.is-workbench-compact .nbd1-controls-grid,
main.is-workbench-compact .nbd1-viz-wrapper,
main.is-workbench-compact .seq-controls-bar,
main.is-workbench-compact .seq-viz-wrap,
main.is-workbench-compact .intronic-controls-bar,
main.is-workbench-compact .intronic-viz-box,
main.is-workbench-compact .ptc-sim-grid,
main.is-workbench-compact .trial-decoder-controls-grid,
main.is-workbench-compact .trial-washout-svg-card,
main.is-workbench-compact .endpoint-tabs-list,
main.is-workbench-compact .endpoint-panels-wrap,
main.is-workbench-compact .cooccurrence-top-pairs-wrap,
main.is-workbench-compact .care-trials-sheet-panel,
main.is-workbench-compact .ptc-schematic-wrap,
main.is-workbench-compact .equity-controls-row,
main.is-workbench-compact .equity-viz-grid,
main.is-workbench-compact .pathway-controls-bar,
main.is-workbench-compact .concordance-controls-row,
main.is-workbench-compact .concordance-svg-wrap,
main.is-workbench-compact .observatory-svg-wrap,
main.is-workbench-compact .sitemap-constellation-svg-wrap {
  display: none !important;
}

section[data-discipline][hidden] {
  display: none !important;
}

section[data-trials-discipline][hidden] {
  display: none !important;
}

@media (prefers-reduced-motion: reduce) {
  .persona-deck-panel:not([hidden]),
  .persona-deck-link,
  main section.is-persona-dimmed {
    transition: none !important;
  }
}

/* === Wave 21 Flagship Discovery: AlphaEvolve-CF Pareto & Formal Invariant Engine (T-0426) === */
.ae-flagship-card {
  margin: 1.5rem 0 2rem;
  padding: 1.5rem;
  border-radius: 14px;
  border: 1px solid rgba(56, 189, 248, 0.35);
  background: linear-gradient(165deg, rgba(10, 18, 32, 0.94) 0%, rgba(7, 13, 24, 0.98) 100%);
  box-shadow: 0 12px 34px rgba(0, 0, 0, 0.45);
}
.ae-flagship-header h3 {
  margin: 0.45rem 0 0.55rem;
  font-size: clamp(1.18rem, 2vw, 1.5rem);
  color: #f8fafc;
}
.ae-flagship-badge-row {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
  align-items: center;
}
.ae-flagship-eyebrow {
  font-family: var(--font-mono, monospace);
  font-size: 0.74rem;
  font-weight: 600;
  letter-spacing: 0.04em;
  text-transform: uppercase;
  padding: 0.22rem 0.6rem;
  border-radius: 999px;
  background: rgba(16, 185, 129, 0.16);
  color: #6ee7b7;
  border: 1px solid rgba(16, 185, 129, 0.4);
}
.ae-tier-pill {
  font-family: var(--font-mono, monospace);
  font-size: 0.72rem;
  padding: 0.2rem 0.55rem;
  border-radius: 999px;
  background: rgba(56, 189, 248, 0.12);
  color: #bae6fd;
  border: 1px solid rgba(56, 189, 248, 0.3);
}
.ae-flagship-lead {
  margin: 0 0 1rem;
  font-size: 0.94rem;
  line-height: 1.55;
  color: #cbd5e1;
}
.ae-presets-bar {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
  margin-bottom: 1rem;
}
.ae-preset-btn {
  font-family: var(--font-mono, monospace);
  font-size: 0.78rem;
  padding: 0.45rem 0.75rem;
  border-radius: 8px;
  border: 1px solid rgba(148, 163, 184, 0.3);
  background: rgba(15, 23, 42, 0.85);
  color: #e2e8f0;
  cursor: pointer;
}
.ae-preset-btn[aria-pressed="true"] {
  border-color: #38bdf8;
  background: rgba(56, 189, 248, 0.18);
  color: #f8fafc;
}
.ae-preset-btn-evolve {
  border-color: rgba(16, 185, 129, 0.45);
  color: #a7f3d0;
}
.ae-controls-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(220px, 1fr));
  gap: 0.75rem;
  margin-bottom: 1rem;
}
.ae-slider-box {
  padding: 0.65rem 0.8rem;
  border-radius: 8px;
  background: rgba(15, 23, 42, 0.7);
  border: 1px solid rgba(148, 163, 184, 0.2);
}
.ae-slider-label-row {
  display: flex;
  justify-content: space-between;
  align-items: baseline;
  gap: 0.4rem;
  font-size: 0.78rem;
  color: #cbd5e1;
  margin-bottom: 0.35rem;
}
.ae-slider-label-row output {
  font-family: var(--font-mono, monospace);
  font-weight: 600;
  color: #38bdf8;
}
.ae-slider-box input[type="range"] {
  width: 100%;
  accent-color: #38bdf8;
}
.ae-kpi-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(175px, 1fr));
  gap: 0.65rem;
  margin-bottom: 0.85rem;
}
.ae-kpi-card {
  padding: 0.6rem 0.75rem;
  border-radius: 8px;
  background: rgba(15, 23, 42, 0.85);
  border: 1px solid rgba(148, 163, 184, 0.22);
  display: flex;
  flex-direction: column;
  gap: 0.2rem;
}
.ae-kpi-label {
  font-size: 0.72rem;
  color: #94a3b8;
}
.ae-kpi-value {
  font-family: var(--font-mono, monospace);
  font-size: 0.92rem;
  color: #f8fafc;
}
.ae-kpi-value[data-smt-state="sat"] {
  color: #6ee7b7;
}
.ae-kpi-value[data-smt-state="unsat"] {
  color: #fca5a5;
}
.ae-invariants-strip {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(215px, 1fr));
  gap: 0.55rem;
  margin-bottom: 0.75rem;
}
.ae-inv-item {
  padding: 0.5rem 0.65rem;
  border-radius: 8px;
  background: rgba(15, 23, 42, 0.65);
  border: 1px solid rgba(148, 163, 184, 0.2);
  display: flex;
  flex-direction: column;
  gap: 0.2rem;
}
.ae-inv-title {
  font-size: 0.73rem;
  color: #cbd5e1;
}
.ae-inv-badge {
  font-family: var(--font-mono, monospace);
  font-size: 0.74rem;
  font-weight: 600;
}
.ae-inv-badge[data-inv-status="pass"] {
  color: #6ee7b7;
}
.ae-inv-badge[data-inv-status="fail"] {
  color: #fca5a5;
}
.ae-unsat-banner {
  margin: 0 0 1rem;
  padding: 0.55rem 0.8rem;
  border-radius: 8px;
  font-family: var(--font-mono, monospace);
  font-size: 0.76rem;
  background: rgba(16, 185, 129, 0.12);
  border: 1px solid rgba(16, 185, 129, 0.35);
  color: #a7f3d0;
}
.ae-unsat-banner[data-proof-state="unsat"] {
  background: rgba(239, 68, 68, 0.14);
  border-color: rgba(239, 68, 68, 0.45);
  color: #fecaca;
}
.ae-svg-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
  gap: 0.9rem;
  margin-bottom: 1rem;
}
.ae-svg-figure {
  margin: 0;
  padding: 0.75rem;
  border-radius: 10px;
  background: rgba(15, 23, 42, 0.8);
  border: 1px solid rgba(148, 163, 184, 0.22);
}
.ae-svg-head {
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  align-items: center;
  gap: 0.5rem;
  margin-bottom: 0.45rem;
  font-size: 0.8rem;
  color: #e2e8f0;
}
.ae-svg-actions {
  display: inline-flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 0.4rem;
}
.ae-svg-figure svg {
  width: 100%;
  height: auto;
  display: block;
}
.ae-svg-bg {
  fill: #070d19;
}
.ae-svg-axis {
  stroke: #475569;
  stroke-width: 1.2;
}
.ae-svg-threshold {
  stroke: #38bdf8;
  stroke-width: 1;
  stroke-dasharray: 4 3;
  opacity: 0.65;
}
.ae-svg-note {
  fill: #94a3b8;
  font-size: 9.5px;
  font-family: monospace;
}
.ae-svg-axis-label {
  fill: #cbd5e1;
  font-size: 10px;
  font-family: monospace;
}
.ae-svg-pt-dominated {
  fill: #f87171;
  opacity: 0.55;
}
.ae-svg-pt-pareto {
  fill: #34d399;
  stroke: #052e16;
  stroke-width: 1.2;
}
.ae-svg-pareto-curve {
  fill: none;
  stroke: #38bdf8;
  stroke-width: 2;
}
.ae-svg-active-ring-sat {
  fill: none;
  stroke: #34d399;
  stroke-width: 2;
}
.ae-svg-active-ring-unsat {
  fill: none;
  stroke: #f87171;
  stroke-width: 2;
}
.ae-svg-active-dot-sat {
  fill: #38bdf8;
}
.ae-svg-active-dot-unsat {
  fill: #ef4444;
}
.ae-svg-active-label,
.ae-svg-ev-label {
  fill: #f8fafc;
  font-size: 10px;
  font-family: monospace;
}
.ae-svg-window-sat {
  fill: rgba(16, 185, 129, 0.2);
  stroke: #34d399;
  stroke-width: 1;
}
.ae-svg-window-unsat {
  fill: rgba(239, 68, 68, 0.18);
  stroke: #f87171;
  stroke-width: 1;
}
.ae-svg-ev-line-sat {
  stroke: #38bdf8;
  stroke-width: 1.4;
}
.ae-svg-ev-line-unsat {
  stroke: #f87171;
  stroke-width: 1.4;
  stroke-dasharray: 3 2;
}
.ae-svg-caption {
  margin-top: 0.4rem;
  font-size: 0.72rem;
  color: #94a3b8;
}
.ae-care-questions {
  padding-top: 0.75rem;
  border-top: 1px solid rgba(148, 163, 184, 0.2);
}
.ae-care-questions h4 {
  margin: 0 0 0.45rem;
  font-size: 0.9rem;
  color: #e2e8f0;
}
.ae-care-list {
  margin: 0 0 0.65rem;
  padding-left: 1.1rem;
  font-size: 0.83rem;
  color: #cbd5e1;
  line-height: 1.5;
}
.ae-boundary-note {
  margin: 0;
  font-size: 0.75rem;
  color: #94a3b8;
}

.ae-preset-btn {
  min-height: 44px;
  display: inline-flex;
  align-items: center;
}
.ae-preset-btn:focus-visible,
.ae-slider-box input[type="range"]:focus-visible {
  outline: 2px solid #38bdf8;
  outline-offset: 2px;
}
@keyframes ae-pulse {
  0%, 100% { opacity: 0.65; }
  50% { opacity: 1; }
}
.ae-svg-active-ring-sat {
  animation: ae-pulse 2.2s ease-in-out infinite;
}
.is-anim-paused .ae-svg-active-ring-sat,
.is-svg-paused .ae-svg-active-ring-sat {
  animation-play-state: paused !important;
}
@media (prefers-reduced-motion: reduce) {
  .ae-svg-active-ring-sat {
    animation: none !important;
  }
}

.ae-svg-hv-poly {
  fill: rgba(56, 189, 248, 0.12);
  stroke: none;
}
.ae-svg-ode-pore {
  fill: none;
  stroke: #34d399;
  stroke-width: 1.8;
  opacity: 0.85;
}
.ae-svg-ode-asl {
  fill: none;
  stroke: #a78bfa;
  stroke-width: 1.6;
  stroke-dasharray: 4 2;
  opacity: 0.85;
}
.ae-svg-ci-ribbon {
  fill: rgba(52, 211, 153, 0.16);
  stroke: rgba(52, 211, 153, 0.38);
  stroke-width: 0.8;
}
.ae-gpu-telemetry-badge {
  margin: 0.35rem 0 0.75rem;
  padding: 0.4rem 0.65rem;
  border-radius: 6px;
  background: rgba(15, 23, 42, 0.72);
  border: 1px solid rgba(56, 189, 248, 0.32);
  font-family: var(--font-mono, monospace);
  font-size: 0.76rem;
  color: #7dd3fc;
}
.ae-protocol-receipt {
  margin: 0.45rem 0 0.85rem;
  padding: 0.7rem;
  border-radius: 6px;
  background: #090f1d;
  border: 1px solid rgba(52, 211, 153, 0.4);
  color: #a7f3d0;
  font-size: 0.74rem;
  max-height: 220px;
  overflow: auto;
}
.ae-forensics-deck {
  margin: 0.9rem 0;
  padding: 0.85rem;
  border-radius: 8px;
  background: rgba(15, 23, 42, 0.68);
  border: 1px solid rgba(148, 163, 184, 0.25);
}
.ae-forensics-deck h4 {
  margin: 0 0 0.35rem;
  font-size: 0.92rem;
  color: #f8fafc;
}
.ae-forensics-lead {
  margin: 0 0 0.65rem;
  font-size: 0.8rem;
  color: #cbd5e1;
}
.ae-forensics-compare-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(240px, 1fr));
  gap: 0.65rem;
  margin: 0.65rem 0;
}
.ae-forensics-box {
  padding: 0.65rem;
  border-radius: 6px;
  font-size: 0.78rem;
  line-height: 1.45;
}
.ae-forensics-unsat {
  background: rgba(127, 29, 29, 0.28);
  border: 1px solid rgba(248, 113, 113, 0.45);
  color: #fecaca;
}
.ae-forensics-sat {
  background: rgba(6, 78, 59, 0.28);
  border: 1px solid rgba(52, 211, 153, 0.45);
  color: #d1fae5;
}
.ae-forensics-actions {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
  align-items: center;
  margin-top: 0.65rem;
}
.ae-forensic-deep-link {
  text-decoration: none;
  display: inline-flex;
  align-items: center;
  gap: 0.35rem;
  background: rgba(30, 41, 59, 0.9);
  color: #38bdf8;
  border: 1px solid rgba(56, 189, 248, 0.45);
  cursor: pointer;
  transition: background 0.15s ease, border-color 0.15s ease, color 0.15s ease;
}
.ae-forensic-deep-link:hover,
.ae-forensic-deep-link:focus-visible {
  background: rgba(56, 189, 248, 0.18);
  border-color: #38bdf8;
  color: #f0f9ff;
}
.ae-smt-repair-banner {
  margin: 0 0 0.65rem;
  padding: 0.5rem 0.75rem;
  border-radius: 8px;
  font-family: var(--font-mono, monospace);
  font-size: 0.75rem;
  background: rgba(15, 23, 42, 0.82);
  border: 1px solid rgba(56, 189, 248, 0.35);
  color: #bae6fd;
}
.ae-smt-repair-banner[data-repair-state="needed"] {
  background: rgba(245, 158, 11, 0.14);
  border-color: rgba(251, 191, 36, 0.48);
  color: #fde68a;
}
.ae-smt-repair-banner[data-repair-state="repaired"] {
  background: rgba(16, 185, 129, 0.16);
  border-color: rgba(52, 211, 153, 0.5);
  color: #a7f3d0;
}
.ae-svg-hud-box {
  fill: rgba(7, 13, 25, 0.92);
  stroke: rgba(56, 189, 248, 0.45);
  stroke-width: 1;
}
.ae-svg-leader {
  stroke: rgba(56, 189, 248, 0.55);
  stroke-width: 1;
  stroke-dasharray: 2 2;
}
.ae-svg-label-bg {
  fill: rgba(7, 13, 25, 0.88);
  stroke: rgba(148, 163, 184, 0.28);
  stroke-width: 0.8;
}
.ae-svg-legend-note {
  fill: #7dd3fc;
  font-size: 7.9px;
  font-family: monospace;
}
.ae-svg-pt-pareto {
  cursor: pointer;
}
.ae-svg-pt-pareto:focus-visible {
  outline: 2px solid #38bdf8;
}
.ae-svg-sobol-add {
  fill: #64748b;
}
.ae-svg-sobol-i12 {
  fill: #38bdf8;
}
.ae-svg-sobol-i34 {
  fill: #34d399;
}
.ae-svg-sobol-i5 {
  fill: #a78bfa;
}
.ae-svg-sobol-i6 {
  fill: #10b981;
}
.ae-svg-sobol-text {
  fill: #cbd5e1;
  font-size: 7.7px;
  font-family: monospace;
}
.ae-webgl-stage {
  margin: 0.9rem 0;
  padding: 0.85rem;
  border-radius: 10px;
  background: rgba(10, 17, 32, 0.86);
  border: 1px solid rgba(56, 189, 248, 0.3);
}
.ae-webgl-stage-head {
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  align-items: flex-start;
  gap: 0.65rem;
  margin-bottom: 0.6rem;
}
.ae-webgl-stage-head strong {
  font-size: 0.88rem;
  color: #f8fafc;
}
.ae-webgl-sub {
  margin: 0.25rem 0 0;
  font-size: 0.78rem;
  color: #cbd5e1;
  max-width: 68ch;
}
.ae-webgl-mode-bar {
  display: flex;
  flex-wrap: wrap;
  gap: 0.45rem;
  align-items: center;
}
.ae-webgl-canvas-wrap {
  width: 100%;
  aspect-ratio: 21 / 9;
  height: auto;
  min-width: 0;
  overflow: hidden;
  border-radius: 8px;
  border: 1px solid rgba(148, 163, 184, 0.25);
  background: #050a14;
}
@media (max-width: 1024px) {
  .ae-webgl-canvas-wrap {
    aspect-ratio: 16 / 9;
    min-height: 210px;
  }
}
@media (max-width: 640px) {
  .ae-webgl-canvas-wrap {
    aspect-ratio: 16 / 10;
    min-height: 195px;
  }
}
#ae-webgl-canvas {
  width: 100%;
  height: 100%;
  display: block;
  touch-action: pan-y;
  cursor: grab;
}
#ae-webgl-canvas:active {
  cursor: grabbing;
}
#ae-webgl-canvas:focus-visible {
  outline: 2px solid #38bdf8;
  outline-offset: -2px;
}
.ae-webgl-controls-bar {
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  align-items: center;
  gap: 0.65rem;
  margin-top: 0.55rem;
}
.ae-webgl-hud-readout {
  font-family: var(--font-mono, monospace);
  font-size: 0.74rem;
  color: #6ee7b7;
}
.ae-webgl-rot-controls {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 0.5rem;
  font-size: 0.74rem;
  color: #cbd5e1;
}
.ae-webgl-rot-controls input[type="range"] {
  width: 96px;
  accent-color: #38bdf8;
}
.ae-waterfall-head {
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  align-items: center;
  gap: 0.5rem;
  margin-bottom: 0.35rem;
}
.ae-waterfall-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(310px, 1fr));
  gap: 0.6rem;
  margin-top: 0.55rem;
}
.ae-wf-card {
  padding: 0.6rem 0.7rem;
  border-radius: 8px;
  background: rgba(15, 23, 42, 0.85);
  border: 1px solid rgba(52, 211, 153, 0.28);
  display: flex;
  flex-direction: column;
  gap: 0.3rem;
}
.ae-wf-card[data-gate-status="bottleneck"] {
  border-color: rgba(248, 113, 113, 0.65);
  background: rgba(127, 29, 29, 0.22);
}
.ae-wf-top {
  display: flex;
  justify-content: space-between;
  align-items: baseline;
  gap: 0.4rem;
  font-size: 0.75rem;
  color: #f8fafc;
}
.ae-wf-val {
  font-family: var(--font-mono, monospace);
  font-size: 0.73rem;
  font-weight: 600;
  color: #6ee7b7;
}
.ae-wf-card[data-gate-status="bottleneck"] .ae-wf-val {
  color: #fca5a5;
}
.ae-wf-meter-svg {
  width: 100%;
  height: 6px;
  display: block;
}
.ae-wf-meter-bg {
  fill: rgba(148, 163, 184, 0.2);
}
.ae-wf-bar-fill {
  fill: #34d399;
}
.ae-wf-card[data-gate-status="bottleneck"] .ae-wf-bar-fill {
  fill: #f87171;
}
.ae-wf-sub {
  font-size: 0.71rem;
  color: #94a3b8;
  line-height: 1.35;
}
@media (max-width: 900px) {
  .ae-webgl-controls-bar {
    flex-direction: column;
    align-items: flex-start;
  }
  .ae-webgl-rot-controls {
    width: 100%;
    justify-content: space-between;
  }
}
@media (max-width: 640px) {
  .ae-flagship-card {
    padding: 1rem 0.75rem;
  }
  .ae-waterfall-grid,
  .ae-svg-grid,
  .ae-controls-grid,
  .ae-invariants-strip {
    grid-template-columns: 1fr;
  }
}

#ae-pareto-svg .ae-svg-hv-poly { fill: url(#ae-hv-gradient); }
#ae-pareto-svg .ae-svg-ci-ribbon { fill: url(#ae-ci-gradient); }
#ae-pareto-svg .ae-svg-active-ring-sat { filter: url(#ae-pareto-node-glow); }
#ae-schedule-svg .ae-svg-window-sat { fill: url(#ae-thixo-window-grad); }
#ae-schedule-svg .ae-svg-ci-ribbon { fill: url(#ae-asl-ribbon-grad); }
[data-status="positive"], [data-status="restored"] { color: #00f3ff; }
[data-status="marginal"] { color: #ffb020; }
[data-status="negative"], [data-status="collapsed"] { color: #f43f5e; }