Independent · Donated time · Open research
Sensei Ewok Research Lab
Small tools. Careful questions. Research in the open.
- What this isA small, independent software lab. We write research tools, test them in public, and say plainly what each one does and does not do.
- What it is notNot a medical organization, not a clinic, and not affiliated with the Cystic Fibrosis Foundation. Nothing here is medical advice.
Interactive 3D Article · Structure 6MSM & C.01
CFTR is a human protein, and variants of it are linked to cystic fibrosis. Structure 6MSM places 1,181 of its 1,480 amino acids. Residue 508 is present in this structure. A model fitted to electron-microscope data, not a photograph.
Structure 6MSM domain color key & provenance
- Membrane-spanning part 1, residues 81 to 365
- Nucleotide-binding part 1, residues 423 to 646
- Membrane-spanning part 2, residues 859 to 1155
- Nucleotide-binding part 2, residues 1210 to 1443
- Gray: placed, outside the four marked parts
- Dotted gray: not placed in this structure
- Flat band: helix or strand, as UniProt annotates
Figure 1. The CFTR protein, drawn from structure 6MSM.
source PDB 6MSM · UniProt P13569 ·
method alpha-carbon trace, residues placed from the deposited coordinates ·
read 2026-10-15 ·
lock 7490af5 ·
not shown movement, lipids, water, or how any variant behaves in a person.
